4lqy: Difference between revisions
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{{STRUCTURE_4lqy| PDB=4lqy | SCENE= }} | |||
===Crystal Structure of Human ENPP4 with AMP=== | |||
{{ABSTRACT_PUBMED_22995898}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/ENPP4_HUMAN ENPP4_HUMAN]] Hydrolyzes extracellular Ap3A into AMP and ADP, and Ap4A into AMP and ATP. Ap3A and Ap4A are diadenosine polyphosphates thought to induce proliferation of vascular smooth muscle cells. Acts as a procoagulant, mediating platelet aggregation at the site of nascent thrombus via release of ADP from Ap3A and activation of ADP receptors.<ref>PMID:22995898</ref> | |||
==About this Structure== | |||
[[4lqy]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LQY OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:022995898</ref><references group="xtra"/><references/> | |||
[[Category: Albright, R A.]] | |||
[[Category: Braddock, D T.]] | |||
[[Category: Enpp4]] | |||
[[Category: Hydrolase]] | |||
[[Category: Npp4]] | |||
[[Category: Phosphodiesterase]] | |||