4mgr: Difference between revisions
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{{STRUCTURE_4mgr| PDB=4mgr | SCENE= }} | |||
===The crystal structure of Bacillus subtilis GabR, an autorepressor and PLP- and GABA-dependent transcriptional activator of gabT=== | |||
{{ABSTRACT_PUBMED_24127574}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/GABR_BACSU GABR_BACSU]] Activates the transcription of the gabTD operon. Is also a repressor of its own expression, both in the presence and absence of GABA. Binds specifically to the DNA region overlapping the -35 region of the gabT promoter and the -10 and +1 regions of the gabR promoter. Principally regulates the utilization of gamma-aminobutyrate.<ref>PMID:12123465</ref> <ref>PMID:15223311</ref> | |||
==About this Structure== | |||
[[4mgr]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MGR OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:024127574</ref><references group="xtra"/><references/> | |||
[[Category: Bacillus subtilis]] | |||
[[Category: Bach, A.]] | |||
[[Category: Belitsky, B R.]] | |||
[[Category: Edayathumangalam, R.]] | |||
[[Category: Garcia, R.]] | |||
[[Category: Hoang, Q Q.]] | |||
[[Category: Kreinbring, C A.]] | |||
[[Category: Liao, J.]] | |||
[[Category: Liu, D.]] | |||
[[Category: Petsko, G A.]] | |||
[[Category: Ringe, D.]] | |||
[[Category: Stone, T.]] | |||
[[Category: Terwilliger, T.]] | |||
[[Category: Wang, W.]] | |||
[[Category: Wang, Y.]] | |||
[[Category: Wu, R.]] | |||
[[Category: Dna binding]] | |||
[[Category: Plp binding]] | |||
[[Category: Transcription regulator]] | |||
[[Category: Type-i aminotransferase]] | |||
[[Category: Winged helix turn helix]] | |||