2o3u: Difference between revisions

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[[Image:2o3u.gif|left|200px]]<br /><applet load="2o3u" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2o3u.gif|left|200px]]
caption="2o3u, resolution 2.11&Aring;" />
 
'''Structural Basis for Formation and Hydrolysis of Calcium Messenger Cyclic ADP-ribose by Human CD38'''<br />
{{Structure
|PDB= 2o3u |SIZE=350|CAPTION= <scene name='initialview01'>2o3u</scene>, resolution 2.11&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=NGD:3-(AMINOCARBONYL)-1-[(2R,3R,4S,5R)-5-({[(S)-{[(S)-{[(2R,3S,4R,5R)-5-(2-AMINO-6-OXO-1,6-DIHYDRO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHOXY}(HYDROXY)PHOSPHORYL]OXY}(HYDROXY)PHOSPHORYL]OXY}METHYL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]PYRIDINIUM'>NGD</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/NAD(+)_nucleosidase NAD(+) nucleosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.5 3.2.2.5]
|GENE= CD38 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''Structural Basis for Formation and Hydrolysis of Calcium Messenger Cyclic ADP-ribose by Human CD38'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2O3U is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=NGD:'>NGD</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/NAD(+)_nucleosidase NAD(+) nucleosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.5 3.2.2.5] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O3U OCA].  
2O3U is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O3U OCA].  


==Reference==
==Reference==
Structural basis for formation and hydrolysis of the calcium messenger cyclic ADP-ribose by human CD38., Liu Q, Kriksunov IA, Graeff R, Lee HC, Hao Q, J Biol Chem. 2007 Feb 23;282(8):5853-61. Epub 2006 Dec 20. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17182614 17182614]
Structural basis for formation and hydrolysis of the calcium messenger cyclic ADP-ribose by human CD38., Liu Q, Kriksunov IA, Graeff R, Lee HC, Hao Q, J Biol Chem. 2007 Feb 23;282(8):5853-61. Epub 2006 Dec 20. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17182614 17182614]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: NAD(+) nucleosidase]]
[[Category: NAD(+) nucleosidase]]
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[[Category: the catalytic pocket]]
[[Category: the catalytic pocket]]


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