2o3z: Difference between revisions

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[[Image:2o3z.gif|left|200px]]<br /><applet load="2o3z" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2o3z.gif|left|200px]]
caption="2o3z, resolution 2.25&Aring;" />
 
'''X-ray crystal structure of LpxC complexed with 3-heptyloxybenzoate'''<br />
{{Structure
|PDB= 2o3z |SIZE=350|CAPTION= <scene name='initialview01'>2o3z</scene>, resolution 2.25&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene> and <scene name='pdbligand=AI7:3-(heptyloxy)benzoic acid'>AI7</scene>
|ACTIVITY=
|GENE= lpxC, envA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=63363 Aquifex aeolicus])
}}
 
'''X-ray crystal structure of LpxC complexed with 3-heptyloxybenzoate'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2O3Z is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Aquifex_aeolicus Aquifex aeolicus] with <scene name='pdbligand=SO4:'>SO4</scene>, <scene name='pdbligand=ZN:'>ZN</scene>, <scene name='pdbligand=CL:'>CL</scene> and <scene name='pdbligand=AI7:'>AI7</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O3Z OCA].  
2O3Z is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Aquifex_aeolicus Aquifex aeolicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O3Z OCA].  


==Reference==
==Reference==
Amphipathic benzoic acid derivatives: synthesis and binding in the hydrophobic tunnel of the zinc deacetylase LpxC., Shin H, Gennadios HA, Whittington DA, Christianson DW, Bioorg Med Chem. 2007 Apr 1;15(7):2617-23. Epub 2007 Jan 31. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17296300 17296300]
Amphipathic benzoic acid derivatives: synthesis and binding in the hydrophobic tunnel of the zinc deacetylase LpxC., Shin H, Gennadios HA, Whittington DA, Christianson DW, Bioorg Med Chem. 2007 Apr 1;15(7):2617-23. Epub 2007 Jan 31. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17296300 17296300]
[[Category: Aquifex aeolicus]]
[[Category: Aquifex aeolicus]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: lpxc]]
[[Category: lpxc]]


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