2o4p: Difference between revisions

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[[Image:2o4p.gif|left|200px]]<br /><applet load="2o4p" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2o4p.gif|left|200px]]
caption="2o4p, resolution 1.80&Aring;" />
 
'''Crystal Structure of HIV-1 Protease (Q7K) in Complex with Tipranavir'''<br />
{{Structure
|PDB= 2o4p |SIZE=350|CAPTION= <scene name='initialview01'>2o4p</scene>, resolution 1.80&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=TPV:N-(3-{(1R)-1-[(6R)-4-HYDROXY-2-OXO-6-PHENETHYL-6-PROPYL-5,6-DIHYDRO-2H-PYRAN-3-YL]PROPYL}PHENYL)-5-(TRIFLUOROMETHYL)-2-PYRIDINESULFONAMIDE'>TPV</scene> and <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>
|ACTIVITY=
|GENE= gag-pol ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11676 Human immunodeficiency virus 1])
}}
 
'''Crystal Structure of HIV-1 Protease (Q7K) in Complex with Tipranavir'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2O4P is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1] with <scene name='pdbligand=TPV:'>TPV</scene> and <scene name='pdbligand=GOL:'>GOL</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O4P OCA].  
2O4P is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O4P OCA].  


==Reference==
==Reference==
Unique thermodynamic response of tipranavir to human immunodeficiency virus type 1 protease drug resistance mutations., Muzammil S, Armstrong AA, Kang LW, Jakalian A, Bonneau PR, Schmelmer V, Amzel LM, Freire E, J Virol. 2007 May;81(10):5144-54. Epub 2007 Mar 14. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17360759 17360759]
Unique thermodynamic response of tipranavir to human immunodeficiency virus type 1 protease drug resistance mutations., Muzammil S, Armstrong AA, Kang LW, Jakalian A, Bonneau PR, Schmelmer V, Amzel LM, Freire E, J Virol. 2007 May;81(10):5144-54. Epub 2007 Mar 14. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17360759 17360759]
[[Category: Human immunodeficiency virus 1]]
[[Category: Human immunodeficiency virus 1]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: protease]]
[[Category: protease]]


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Retrieved from "https://proteopedia.org/2o4p"