2o4k: Difference between revisions
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[[Image:2o4k.gif|left|200px]] | [[Image:2o4k.gif|left|200px]] | ||
'''Crystal Structure of HIV-1 Protease (Q7K) in Complex with Atazanavir''' | {{Structure | ||
|PDB= 2o4k |SIZE=350|CAPTION= <scene name='initialview01'>2o4k</scene>, resolution 1.600Å | |||
|SITE= | |||
|LIGAND= <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene> and <scene name='pdbligand=DR7:(3S,8S,9S,12S)-3,12-BIS(1,1-DIMETHYLETHYL)-8-HYDROXY-4,11-DIOXO-9-(PHENYLMETHYL)-6-[[4-(2-PYRIDINYL)PHENYL]METHYL]-2,5,6,10,13-PENTAAZATETRADECANEDIOIC ACID DIMETHYL ESTER'>DR7</scene> | |||
|ACTIVITY= | |||
|GENE= gag-pol ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11676 Human immunodeficiency virus 1]) | |||
}} | |||
'''Crystal Structure of HIV-1 Protease (Q7K) in Complex with Atazanavir''' | |||
==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
2O4K is a [ | 2O4K is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O4K OCA]. | ||
==Reference== | ==Reference== | ||
Unique thermodynamic response of tipranavir to human immunodeficiency virus type 1 protease drug resistance mutations., Muzammil S, Armstrong AA, Kang LW, Jakalian A, Bonneau PR, Schmelmer V, Amzel LM, Freire E, J Virol. 2007 May;81(10):5144-54. Epub 2007 Mar 14. PMID:[http:// | Unique thermodynamic response of tipranavir to human immunodeficiency virus type 1 protease drug resistance mutations., Muzammil S, Armstrong AA, Kang LW, Jakalian A, Bonneau PR, Schmelmer V, Amzel LM, Freire E, J Virol. 2007 May;81(10):5144-54. Epub 2007 Mar 14. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17360759 17360759] | ||
[[Category: Human immunodeficiency virus 1]] | [[Category: Human immunodeficiency virus 1]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
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[[Category: protease complex]] | [[Category: protease complex]] | ||
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