4c58: Difference between revisions

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'''Unreleased structure'''
{{STRUCTURE_4c58|  PDB=4c58  |  SCENE=  }}
===Structure of GAK kinase in complex with nanobody (NbGAK_4)===


The entry 4c58 is ON HOLD
==Function==
[[http://www.uniprot.org/uniprot/GAK_HUMAN GAK_HUMAN]] Associates with cyclin G and CDK5. Seems to act as an auxilin homolog that is involved in the uncoating of clathrin-coated vesicles by Hsc70 in non-neuronal cells. Expression oscillates slightly during the cell cycle, peaking at G1.<ref>PMID:10625686</ref> 


Authors: Chaikuad, A., Keates, T., Allerston, C.K., Gileadi, O., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Knapp, S., Muller-Knapp, S.
==About this Structure==
[[4c58]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4C58 OCA].  


Description: Structure of GAK kinase in complex with nanobody (NbGAK_4)
==Reference==
<references group="xtra"/><references/>
[[Category: Homo sapiens]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Allerston, C K.]]
[[Category: Arrowsmith, C H.]]
[[Category: Bountra, C.]]
[[Category: Chaikuad, A.]]
[[Category: Delft, F von.]]
[[Category: Edwards, A M.]]
[[Category: Gileadi, O.]]
[[Category: Keates, T.]]
[[Category: Knapp, S.]]
[[Category: Muller-Knapp, S.]]
[[Category: Activation]]
[[Category: Conformational plasticity]]
[[Category: Kinase]]
[[Category: Transferase]]
Retrieved from "https://proteopedia.org/4c58"