4mjw: Difference between revisions
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{{STRUCTURE_4mjw| PDB=4mjw | SCENE= }} | |||
===Crystal Structure of Choline Oxidase in Complex with the Reaction Product Glycine Betaine=== | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/CHOX_ARTGO CHOX_ARTGO]] Catalyzes the two-step oxidative conversion of choline to glycine-betaine with betaine aldehyde as an intermediate. Glycine-betaine accumulates to high levels in the cytoplasm of cells to prevent dehydration and plasmolysis in adverse hyperosmotic environments. Accepts either choline or the reaction intermediate betaine-aldehyde as substrate.<ref>PMID:12795615</ref> | |||
==About this Structure== | |||
[[4mjw]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MJW OCA]. | |||
==Reference== | |||
<references group="xtra"/><references/> | |||
[[Category: Choline oxidase]] | |||
[[Category: Gadda, G.]] | |||
[[Category: Salvi, F.]] | |||
[[Category: Wang, Y F.]] | |||
[[Category: Weber, I T.]] | |||
[[Category: Choline]] | |||
[[Category: Fad binding]] | |||
[[Category: Glucose-methanol-choline]] | |||
[[Category: Glycine betaine]] | |||
[[Category: Oxidase]] | |||
[[Category: Oxidoreductase]] | |||
[[Category: Reaction product]] | |||
Revision as of 05:21, 13 February 2014
Crystal Structure of Choline Oxidase in Complex with the Reaction Product Glycine Betaine
Function
[CHOX_ARTGO] Catalyzes the two-step oxidative conversion of choline to glycine-betaine with betaine aldehyde as an intermediate. Glycine-betaine accumulates to high levels in the cytoplasm of cells to prevent dehydration and plasmolysis in adverse hyperosmotic environments. Accepts either choline or the reaction intermediate betaine-aldehyde as substrate.[1]
About this Structure
4mjw is a 2 chain structure. Full crystallographic information is available from OCA.
Reference
- ↑ Rand T, Halkier T, Hansen OC. Structural characterization and mapping of the covalently linked FAD cofactor in choline oxidase from Arthrobacter globiformis. Biochemistry. 2003 Jun 17;42(23):7188-94. PMID:12795615 doi:https://dx.doi.org/10.1021/bi0274266
