2oc8: Difference between revisions

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[[Image:2oc8.jpg|left|200px]]<br /><applet load="2oc8" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2oc8.jpg|left|200px]]
caption="2oc8, resolution 2.66&Aring;" />
 
'''Structure of Hepatitis C Viral NS3 protease domain complexed with NS4A peptide and ketoamide SCH503034'''<br />
{{Structure
|PDB= 2oc8 |SIZE=350|CAPTION= <scene name='initialview01'>2oc8</scene>, resolution 2.66&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>, <scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene> and <scene name='pdbligand=HU5:(1R,2S,5S)-N-[(1S)-3-AMINO-1-(CYCLOBUTYLMETHYL)-2,3-DIOXOPROPYL]-3-[(2S)-2-{[(TERT-BUTYLAMINO)CARBONYL]AMINO}-3,3-DIMETHYLBUTANOYL]-6,6-DIMETHYL-3-AZABICYCLO[3.1.0]HEXANE-2-CARBOXAMIDE'>HU5</scene>
|ACTIVITY=
|GENE= NS3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11103 Hepatitis C virus])
}}
 
'''Structure of Hepatitis C Viral NS3 protease domain complexed with NS4A peptide and ketoamide SCH503034'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2OC8 is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Hepatitis_c_virus Hepatitis c virus] with <scene name='pdbligand=ZN:'>ZN</scene>, <scene name='pdbligand=BME:'>BME</scene> and <scene name='pdbligand=HU5:'>HU5</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OC8 OCA].  
2OC8 is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Hepatitis_c_virus Hepatitis c virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OC8 OCA].  


==Reference==
==Reference==
Crystal structure of the hepatitis C virus NS3 protease domain complexed with a synthetic NS4A cofactor peptide., Kim JL, Morgenstern KA, Lin C, Fox T, Dwyer MD, Landro JA, Chambers SP, Markland W, Lepre CA, O'Malley ET, Harbeson SL, Rice CM, Murcko MA, Caron PR, Thomson JA, Cell. 1996 Oct 18;87(2):343-55. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=8861917 8861917]
Crystal structure of the hepatitis C virus NS3 protease domain complexed with a synthetic NS4A cofactor peptide., Kim JL, Morgenstern KA, Lin C, Fox T, Dwyer MD, Landro JA, Chambers SP, Markland W, Lepre CA, O'Malley ET, Harbeson SL, Rice CM, Murcko MA, Caron PR, Thomson JA, Cell. 1996 Oct 18;87(2):343-55. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/8861917 8861917]
[[Category: Hepatitis c virus]]
[[Category: Hepatitis c virus]]
[[Category: Protein complex]]
[[Category: Protein complex]]
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[[Category: viral protein]]
[[Category: viral protein]]


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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 17:57:47 2008''
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