2ocf: Difference between revisions

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[[Image:2ocf.jpg|left|200px]]<br /><applet load="2ocf" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2ocf.jpg|left|200px]]
caption="2ocf, resolution 2.95&Aring;" />
 
'''Human estrogen receptor alpha ligand-binding domain in complex with estradiol and the E2#23 FN3 monobody'''<br />
{{Structure
|PDB= 2ocf |SIZE=350|CAPTION= <scene name='initialview01'>2ocf</scene>, resolution 2.95&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=EST:ESTRADIOL'>EST</scene>
|ACTIVITY=
|GENE= ESR1, ESR, NR3A1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]), CIG, FN1, FN ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''Human estrogen receptor alpha ligand-binding domain in complex with estradiol and the E2#23 FN3 monobody'''
 


==Disease==
==Disease==
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==About this Structure==
==About this Structure==
2OCF is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=EST:'>EST</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OCF OCA].  
2OCF is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OCF OCA].  
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Protein complex]]
[[Category: Protein complex]]
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[[Category: monobody]]
[[Category: monobody]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 18:16:59 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 17:57:53 2008''

Revision as of 15:57, 20 March 2008

File:2ocf.jpg


Drag the structure with the mouse to rotate
2ocf, resolution 2.95Å
Ligands: EST
Gene: ESR1, ESR, NR3A1 (Homo sapiens), CIG, FN1, FN (Homo sapiens)
Coordinates: save as pdb, mmCIF, xml



Human estrogen receptor alpha ligand-binding domain in complex with estradiol and the E2#23 FN3 monobody


Disease

Known diseases associated with this structure: Atherosclerosis, susceptibility to OMIM:[133430], Breast cancer OMIM:[133430], Ehlers-Danlos syndrome, type X, 225310 (1) OMIM:[135600], Estrogen resistance OMIM:[133430], HDL response to hormone replacement, augmented OMIM:[133430], Migraine, susceptibility to OMIM:[133430], Myocardial infarction, susceptibility to OMIM:[133430]

About this Structure

2OCF is a Protein complex structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Page seeded by OCA on Thu Mar 20 17:57:53 2008

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