4c6m: Difference between revisions

Revision as of 10:04, 8 January 2014

[PYR1_HUMAN] This protein is a "fusion" protein encoding four enzymatic activities of the pyrimidine pathway (GATase, CPSase, ATCase and DHOase).

4c6m is a 1 chain structure. Full crystallographic information is available from OCA.

Grande-Garcia A, Lallous N, Diaz-Tejada C, Ramon-Maiques S. Structure, Functional Characterization, and Evolution of the Dihydroorotase Domain of Human CAD. Structure. 2013 Dec 10. pii: S0969-2126(13)00428-0. doi:, 10.1016/j.str.2013.10.016. PMID:24332717 doi:https://dx.doi.org/10.1016/j.str.2013.10.016

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-'''Unreleased structure'''
+{{STRUCTURE_4c6m|  PDB=4c6m  |  SCENE=  }}
+===Crystal structure of the dihydroorotase domain of human CAD bound to the inhibitor fluoroorotate at pH 7.0===
+{{ABSTRACT_PUBMED_24332717}}
-The entry 4c6m is ON HOLD  until Paper Publication
+==Function==
+[[http://www.uniprot.org/uniprot/PYR1_HUMAN PYR1_HUMAN]] This protein is a "fusion" protein encoding four enzymatic activities of the pyrimidine pathway (GATase, CPSase, ATCase and DHOase).
-Authors: Ramon-Maiques, S., Lallous, N., Grande-Garcia, A.
+==About this Structure==
+[[4c6m]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4C6M OCA].
-Description: Crystal structure of the dihydroorotase domain of human CAD bound to the inhibitor fluoroorotate at pH 7.0
+==Reference==
+<ref group="xtra">PMID:024332717</ref><references group="xtra"/><references/>
+[[Category: Dihydroorotase]]
+[[Category: Grande-Garcia, A.]]
+[[Category: Lallous, N.]]
+[[Category: Ramon-Maiques, S.]]
+[[Category: Amidohydrolase superfamily]]
+[[Category: De novo pyrimidine biosynthesis]]
+[[Category: Histidinate anion]]
+[[Category: Hydrolase]]
+[[Category: Metalloenzyme]]
+[[Category: Zinc binding]]