4m47: Difference between revisions

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~~'''Unreleased~~ structure~~'''~~

===structure of human DNA polymerase complexed with 8-BrG in the template base paired with incoming non-hydrolyzable GTP===

~~The entry 4m47 is ON HOLD~~ ~~until Paper Publication~~

==Function==

[[http://www.uniprot.org/uniprot/DPOLB_HUMAN DPOLB_HUMAN]] Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases.<ref>PMID:9207062</ref> <ref>PMID:9572863</ref> <ref>PMID:11805079</ref> <ref>PMID:21362556</ref>

~~Authors~~: ~~Koag, M.C., Min, K~~.~~, Monzingo, A~~.F.~~, Lee, S~~.

==About this Structure==

[[4m47]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M47 OCA].

~~Description~~: ~~structure of human DNA polymerase complexed with 8-BrG in the template base paired with incoming non~~-~~hydrolyzable GTP~~

==Reference==

[[Category: Koag, M C.]]

[[Category: Lee, S.]]

[[Category: Min, K.]]

[[Category: Monzingo, A F.]]

[[Category: Base excision repair]]

[[Category: Dna synthesis]]

[[Category: Transferase-dna complex]]

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-'''Unreleased structure'''
+{{STRUCTURE_4m47|  PDB=4m47  |  SCENE=  }}
+===structure of human DNA polymerase complexed with 8-BrG in the template base paired with incoming non-hydrolyzable GTP===
-The entry 4m47 is ON HOLD  until Paper Publication
+==Function==
+[[http://www.uniprot.org/uniprot/DPOLB_HUMAN DPOLB_HUMAN]] Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases.<ref>PMID:9207062</ref> <ref>PMID:9572863</ref> <ref>PMID:11805079</ref> <ref>PMID:21362556</ref>
-Authors: Koag, M.C., Min, K., Monzingo, A.F., Lee, S.
+==About this Structure==
+[[4m47]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M47 OCA].
-Description: structure of human DNA polymerase complexed with 8-BrG in the template base paired with incoming non-hydrolyzable GTP
+==Reference==
+<references group="xtra"/><references/>
+[[Category: Koag, M C.]]
+[[Category: Lee, S.]]
+[[Category: Min, K.]]
+[[Category: Monzingo, A F.]]
+[[Category: Base excision repair]]
+[[Category: Dna synthesis]]
+[[Category: Transferase-dna complex]]