4m9v: Difference between revisions

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'''Unreleased structure'''
{{STRUCTURE_4m9v|  PDB=4m9v  |  SCENE=  }}
===Zfp57 mutant (E182Q) in complex with 5-carboxylcytosine DNA===
{{ABSTRACT_PUBMED_24236546}}


The entry 4m9v is ON HOLD
==Function==
[[http://www.uniprot.org/uniprot/ZFP57_MOUSE ZFP57_MOUSE]] Transcription regulator required to maintain maternal and paternal gene imprinting, a process by which gene expression is restricted in a parent of origin-specific manner by epigenetic modification of genomic DNA and chromatin, including DNA methylation. Acts by controlling DNA methylation during the earliest multicellular stages of development at multiple imprinting control regions. Required for the establishment of maternal methylation imprints at SNRPN locus. Acts as a transcriptional repressor in Schwann cells. Binds to a 5'-TGCCGC-3' consensus sequence and recognizes the methylated CpG within this element.<ref>PMID:15070898</ref> <ref>PMID:18854139</ref> <ref>PMID:23059534</ref> 


Authors: Liu, Y., Olanrewaju, Y.O., Zhang, X., Cheng, X.
==About this Structure==
[[4m9v]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M9V OCA].  


Description: Zfp57 mutant (E182Q) in complex with 5-carboxylcytosine DNA
==Reference==
<ref group="xtra">PMID:024236546</ref><references group="xtra"/><references/>
[[Category: Cheng, X.]]
[[Category: Liu, Y.]]
[[Category: Olanrewaju, Y O.]]
[[Category: Zhang, X.]]
[[Category: 5-carboxylcytosine]]
[[Category: C2h2 zinc finger]]
[[Category: Dna binding]]
[[Category: Epigenetic]]
[[Category: Transcription factor]]
[[Category: Transcription-dna complex]]
Retrieved from "https://proteopedia.org/4m9v"