2ofx: Difference between revisions

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[[Image:2ofx.gif|left|200px]]<br /><applet load="2ofx" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2ofx.gif|left|200px]]
caption="2ofx, resolution 1.900&Aring;" />
 
'''crystal structure of the APSK domain of human PAPSS1 in complex with ADPMg and PAPS'''<br />
{{Structure
|PDB= 2ofx |SIZE=350|CAPTION= <scene name='initialview01'>2ofx</scene>, resolution 1.900&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=PPS:3'-PHOSPHATE-ADENOSINE-5'-PHOSPHATE+SULFATE'>PPS</scene> and <scene name='pdbligand=ADP:ADENOSINE-5'-DIPHOSPHATE'>ADP</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Adenylyl-sulfate_kinase Adenylyl-sulfate kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.25 2.7.1.25]
|GENE= PAPSS1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''crystal structure of the APSK domain of human PAPSS1 in complex with ADPMg and PAPS'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2OFX is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=MG:'>MG</scene>, <scene name='pdbligand=PO4:'>PO4</scene>, <scene name='pdbligand=PPS:'>PPS</scene> and <scene name='pdbligand=ADP:'>ADP</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Adenylyl-sulfate_kinase Adenylyl-sulfate kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.25 2.7.1.25] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OFX OCA].  
2OFX is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OFX OCA].  


==Reference==
==Reference==
Elucidation of the active conformation of the APS-kinase domain of human PAPS synthetase 1., Sekulic N, Dietrich K, Paarmann I, Ort S, Konrad M, Lavie A, J Mol Biol. 2007 Mar 23;367(2):488-500. Epub 2007 Jan 12. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17276460 17276460]
Elucidation of the active conformation of the APS-kinase domain of human PAPS synthetase 1., Sekulic N, Dietrich K, Paarmann I, Ort S, Konrad M, Lavie A, J Mol Biol. 2007 Mar 23;367(2):488-500. Epub 2007 Jan 12. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17276460 17276460]
[[Category: Adenylyl-sulfate kinase]]
[[Category: Adenylyl-sulfate kinase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: nucleotide kinase]]
[[Category: nucleotide kinase]]


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