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{{STRUCTURE_4mpf|  PDB=4mpf  |  SCENE=  }}
==Crystal structure of human glutathione transferase theta-2, complex with inorganic phosphate, GSH free, target EFI-507257==
===Crystal structure of human glutathione transferase theta-2, complex with inorganic phosphate, GSH free, target EFI-507257===
<StructureSection load='4mpf' size='340' side='right' caption='[[4mpf]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
 
== Structural highlights ==
==Function==
<table><tr><td colspan='2'>[[4mpf]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MPF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4MPF FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=TLA:L(+)-TARTARIC+ACID'>TLA</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4mpg|4mpg]]</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GSTT2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glutathione_transferase Glutathione transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.18 2.5.1.18] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4mpf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mpf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4mpf RCSB], [http://www.ebi.ac.uk/pdbsum/4mpf PDBsum]</span></td></tr>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/GST2_HUMAN GST2_HUMAN]] Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Has a sulfatase activity.  
[[http://www.uniprot.org/uniprot/GST2_HUMAN GST2_HUMAN]] Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Has a sulfatase activity.  


==About this Structure==
==See Also==
[[4mpf]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MPF OCA].
*[[Glutathione S-transferase|Glutathione S-transferase]]
__TOC__
</StructureSection>
[[Category: Glutathione transferase]]
[[Category: Glutathione transferase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Almo, S C.]]
[[Category: Almo, S C]]
[[Category: Armstrong, R N.]]
[[Category: Armstrong, R N]]
[[Category: Bhosle, R.]]
[[Category: Bhosle, R]]
[[Category: Chowdhury, S.]]
[[Category: Chowdhury, S]]
[[Category: EFI, Enzyme Function Initiative.]]
[[Category: EFI, Enzyme Function Initiative]]
[[Category: Evans, B.]]
[[Category: Evans, B]]
[[Category: Gerlt, J A.]]
[[Category: Gerlt, J A]]
[[Category: Glenn, A Scott.]]
[[Category: Glenn, A Scott]]
[[Category: Hammonds, J.]]
[[Category: Hammonds, J]]
[[Category: Hillerich, B.]]
[[Category: Hillerich, B]]
[[Category: Imker, H J.]]
[[Category: Imker, H J]]
[[Category: Love, J.]]
[[Category: Love, J]]
[[Category: Obaidi, N Al.]]
[[Category: Obaidi, N Al]]
[[Category: Patskovsky, Y.]]
[[Category: Patskovsky, Y]]
[[Category: Seidel, R D.]]
[[Category: Seidel, R D]]
[[Category: Stead, M.]]
[[Category: Stead, M]]
[[Category: Toro, R.]]
[[Category: Toro, R]]
[[Category: Washington, E.]]
[[Category: Washington, E]]
[[Category: Efi]]
[[Category: Efi]]
[[Category: Enzyme function initiative]]
[[Category: Enzyme function initiative]]

Revision as of 17:42, 24 December 2014

Crystal structure of human glutathione transferase theta-2, complex with inorganic phosphate, GSH free, target EFI-507257

4mpf, resolution 2.10Å

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