2mdk: Difference between revisions
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{{STRUCTURE_2mdk| PDB=2mdk | SCENE= }} | |||
===NMR Solution Structure of MSP-P56S Domain/VAPB in DPC=== | |||
The entry | ==Disease== | ||
[[http://www.uniprot.org/uniprot/VAPB_HUMAN VAPB_HUMAN]] Adult-onset proximal spinal muscular atrophy, autosomal dominant;Amyotrophic lateral sclerosis. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry. | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/VAPB_HUMAN VAPB_HUMAN]] Participates in the endoplasmic reticulum unfolded protein response (UPR) by inducing ERN1/IRE1 activity. Involved in cellular calcium homeostasis regulation.<ref>PMID:16891305</ref> <ref>PMID:20940299</ref> <ref>PMID:22131369</ref> | |||
==About this Structure== | |||
[[2mdk]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MDK OCA]. | |||
==Reference== | |||
<references group="xtra"/><references/> | |||
[[Category: Homo sapiens]] | |||
[[Category: Lim, L.]] | |||
[[Category: Qin, H.]] | |||
[[Category: Song, J.]] | |||
[[Category: Membrane protein]] | |||
[[Category: Msp-p56s domain]] | |||
[[Category: Vapb]] | |||