4mvt: Difference between revisions

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'''Unreleased structure'''
{{STRUCTURE_4mvt|  PDB=4mvt  |  SCENE=  }}
===Crystal structure of SUMO E3 Ligase PIAS3===


The entry 4mvt is ON HOLD
==Function==
[[http://www.uniprot.org/uniprot/PIAS3_HUMAN PIAS3_HUMAN]] Functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. Plays a crucial role as a transcriptional coregulation in various cellular pathways, including the STAT pathway and the steroid hormone signaling pathway. Involved in regulating STAT3 signaling via inhibiting STAT3 DNA-binding and suppressing cell growth.<ref>PMID:9388184</ref> 


Authors: Dong, A., Hu, J., Li, Y., Tempel, W., Bountra, C., Arrowsmith, C.H., Edwards, A.M., Tong, Y., Structural Genomics Consortium (SGC)
==About this Structure==
[[4mvt]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MVT OCA].  


Description: Crystal structure of SUMO E3 Ligase PIAS3
==Reference==
<references group="xtra"/><references/>
[[Category: Homo sapiens]]
[[Category: Arrowsmith, C H.]]
[[Category: Bountra, C.]]
[[Category: Dong, A.]]
[[Category: Edwards, A M.]]
[[Category: Hu, J.]]
[[Category: Li, Y.]]
[[Category: SGC, Structural Genomics Consortium.]]
[[Category: Tempel, W.]]
[[Category: Tong, Y.]]
[[Category: E3 ligase]]
[[Category: Ligase]]
[[Category: Pinit domain]]
[[Category: Sgc]]
[[Category: Sp-ring domain]]
[[Category: Structural genomic]]
[[Category: Structural genomics consortium]]
[[Category: Sumo]]