2onb: Difference between revisions

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[[Image:2onb.gif|left|200px]]~~<br /><applet load~~="2onb~~" size~~="350~~" color~~=~~"white" frame~~=~~"true" align="right" spinBox="true"~~

[[Image:2onb.gif|left|200px]]

~~caption="~~2onb, resolution 2.700Å" />

'''Human Thymidylate Synthase at low salt conditions with PDPA bound'''~~<br />~~

{{Structure

|PDB= 2onb |SIZE=350|CAPTION= <scene name='initialview01'>2onb</scene>, resolution 2.700Å

|SITE=

|LIGAND= <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene> and <scene name='pdbligand=7PA:PROPANE-1,3-DIYLBIS(PHOSPHONIC ACID)'>7PA</scene>

|ACTIVITY=

|GENE=

}}

'''Human Thymidylate Synthase at low salt conditions with PDPA bound'''

==Overview==

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==About this Structure==

2ONB is a [~~http://en.wikipedia.org/wiki/Single_protein~~ Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens~~] with <scene name='pdbligand=SO4:'>SO4</scene>, <scene name='pdbligand=EDO:'>EDO</scene> and <scene name='pdbligand=7PA:'>7PA</scene> as [http://en.wikipedia.org/wiki/ligands ligands~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ONB OCA].

2ONB is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ONB OCA].

==Reference==

Cooperative inhibition of human thymidylate synthase by mixtures of active site binding and allosteric inhibitors., Lovelace LL, Gibson LM, Lebioda L, Biochemistry. 2007 Mar 13;46(10):2823-30. Epub 2007 Feb 13. PMID:[http://~~ispc~~.~~weizmann~~.ac.~~il/~~/~~pmbin~~/~~getpm?pmid=~~17297914 17297914]

Cooperative inhibition of human thymidylate synthase by mixtures of active site binding and allosteric inhibitors., Lovelace LL, Gibson LM, Lebioda L, Biochemistry. 2007 Mar 13;46(10):2823-30. Epub 2007 Feb 13. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17297914 17297914]

[[Category: Homo sapiens]]

[[Category: Single protein]]

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[[Category: zd9331]]

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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 18:01:59 2008''

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@@ Line 1: / Line 1: @@
-[[Image:2onb.gif|left|200px]]<br /><applet load="2onb" size="350" color="white" frame="true" align="right" spinBox="true"
+[[Image:2onb.gif|left|200px]]
-caption="2onb, resolution 2.700&Aring;" />
-'''Human Thymidylate Synthase at low salt conditions with PDPA bound'''<br />
+ {{Structure
+|PDB= 2onb |SIZE=350|CAPTION= <scene name='initialview01'>2onb</scene>, resolution 2.700&Aring;
+|SITE=
+|LIGAND= <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene> and <scene name='pdbligand=7PA:PROPANE-1,3-DIYLBIS(PHOSPHONIC ACID)'>7PA</scene>
+|ACTIVITY=
+|GENE=
+}}
+'''Human Thymidylate Synthase at low salt conditions with PDPA bound'''
 ==Overview==
@@ Line 7: / Line 16: @@
 ==About this Structure==
-ONB is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=SO4:'>SO4</scene>, <scene name='pdbligand=EDO:'>EDO</scene> and <scene name='pdbligand=7PA:'>7PA</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ONB OCA].
+ONB is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ONB OCA].
 ==Reference==
-Cooperative inhibition of human thymidylate synthase by mixtures of active site binding and allosteric inhibitors., Lovelace LL, Gibson LM, Lebioda L, Biochemistry. 2007 Mar 13;46(10):2823-30. Epub 2007 Feb 13. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17297914 17297914]
+Cooperative inhibition of human thymidylate synthase by mixtures of active site binding and allosteric inhibitors., Lovelace LL, Gibson LM, Lebioda L, Biochemistry. 2007 Mar 13;46(10):2823-30. Epub 2007 Feb 13. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17297914 17297914]
 [[Category: Homo sapiens]]
 [[Category: Single protein]]
@@ Line 24: / Line 33: @@
 [[Category: zd9331]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 18:20:22 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 18:01:59 2008''