ABA-regulated SNRK2 Protein Kinase: Difference between revisions

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New page: ==Kinase names and family members== Two of SnRK2.6/OST1/SRK2E's three names originated from its membership in subclass III of the SnRK2 family of protein kinases. It was named SnRK2.6 by H...
 
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==Kinase names and family members==
==Kinase names and family members==
Two of SnRK2.6/OST1/SRK2E's three names originated from its membership in subclass III of the SnRK2 family of protein kinases. It was named SnRK2.6 by Hrabak et al.<ref>PMID:12805596</ref> and SRK2E by Umezawa et al.<ref name ="Umezawa2009"/>. SnRK2 stands for SNF1-related kinase group 2, which in Arabidopsis has 10 members. SNRK2s are members of the calmodulin-dependent protein kinase clade of protein kinases. The third name OST1 (open stomata 1)<ref name = "Mustilli2002"/> is descriptive of the phenotype of plants bearing a gene mutation that produces an inactive protein kinase.  
Three members of the SnRK2 family of protein kinases - SnRK2.6/OST1/SRK2E, SNRK2.2/SRK2D and SnRK2.3/SRK2I - are activated by the [[ABA Signaling Pathway]]. SnRK2 stands for <u>Sn</u>f1-<u>r</u>elated protein <u>k</u>inase family, group <u>2</u>. These protein kinases have [[Eukaryotic Protein Kinase Catalytic Domain]]s that are related to yeast Snf1, and they belong to the calmodulin-dependent protein kinase family of the kinome.  


Two other family members in Arabidopsis, SNRK2.2/SRK2D and SnRK2.3/SRK2I, are activated by the ABA pathway in the same manner as SnRK2.6. Each of these kinases interacts with a member of clade A of the protein phosphatase 2C family - ABI1, HAB1 or HAB2. In rice homologs of these protein kinases are named SAPK8, SAPK9 and SAPK10.
Two of SnRK2.6/OST1/SRK2E's three names originated from its membership in subclass III of the SnRK2 family of protein kinases. It was named SnRK2.6 by Hrabak et al.<ref>PMID:12805596</ref> and SRK2E by Umezawa et al.<ref name ="Umezawa2009"/>. The third name OST1 (open stomata 1)<ref name = "Mustilli2002"/> is descriptive of the phenotype of plants bearing a gene mutation that produces an inactive protein kinase.  
 
In rice homologs of these protein kinases are named SAPK8, SAPK9 and SAPK10.


==Kinase structure and regulation==
==Kinase structure and regulation==