2mdq: Difference between revisions
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{{STRUCTURE_2mdq| PDB=2mdq | SCENE= }} | |||
===A Novel 4/7-Conotoxin LvIA from Conus lividus that Selectively Blocks 3 2 vs. 6/3 2 3 Nicotinic Acetylcholine Receptors=== | |||
{{ABSTRACT_PUBMED_24398291}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/L8BU87_CONLI L8BU87_CONLI]] Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them (By similarity).[RuleBase:RU004345] | |||
==About this Structure== | |||
[[2mdq]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MDQ OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:024398291</ref><references group="xtra"/><references/> | |||
[[Category: Schroeder, C I.]] | |||
[[Category: Alfa-conotoxin]] | |||
[[Category: Conotoxin]] | |||
[[Category: Disulfide rich]] | |||
[[Category: Nicotinic acetylcholine receptor]] | |||
[[Category: Toxin]] | |||
Revision as of 05:06, 13 February 2014
A Novel 4/7-Conotoxin LvIA from Conus lividus that Selectively Blocks 3 2 vs. 6/3 2 3 Nicotinic Acetylcholine Receptors
Template:ABSTRACT PUBMED 24398291
Function
[L8BU87_CONLI] Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them (By similarity).[RuleBase:RU004345]
About this Structure
2mdq is a 1 chain structure. Full experimental information is available from OCA.
Reference
- Luo S, Zhangsun D, Schroeder CI, Zhu X, Hu Y, Wu Y, Weltzin MM, Eberhard S, Kaas Q, Craik DJ, McIntosh JM, Whiteaker P. A novel alpha4/7-conotoxin LvIA from Conus lividus that selectively blocks alpha3beta2 vs. alpha6/alpha3beta2beta3 nicotinic acetylcholine receptors. FASEB J. 2014 Jan 7. PMID:24398291 doi:https://dx.doi.org/10.1096/fj.13-244103
