4c92: Difference between revisions

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'''Unreleased structure'''
{{STRUCTURE_4c92|  PDB=4c92  |  SCENE=  }}
===Crystal structure of the yeast Lsm1-7 complex===


The entry 4c92 is ON HOLD  until sometime in the future
==Function==
[[http://www.uniprot.org/uniprot/LSM3_YEAST LSM3_YEAST]] Component of LSm protein complexes, which are involved in RNA processing and may function in a chaperone-like manner. Component of the cytoplasmic LSM1-LSM7 complex which is thought to be involved in mRNA degradation by activating the decapping step. Component of the nuclear LSM2-LSM8 complex, which is involved in splicing of nuclear mRNAs. LSM2-LSM8 associates with multiple snRNP complexes containing the U6 snRNA (U4/U6 snRNP, U4/U6.U5 snRNP, and free U6 snRNP). It binds directly to the U6 snRNA and plays a role in the biogenesis and stability of the U6 snRNP and U4/U6 snRNP complexes. It probably also is involved degradation of nuclear pre-mRNA by targeting them for decapping. LSM3 binds specifically to the 3'-terminal U-tract of U6 snRNA. LSM2-LSM8 probably is involved in processing of pre-tRNAs, pre-rRNAs and U3 snoRNA. LSM3, probably in a complex that contains LSM2-LSM7 but not LSM1 or LSM8, associates with the precursor of the RNA component of RNase P (pre-P RNA) and may be involved in maturing pre-P RNA. LSM3 is required for processing of pre-tRNAs, pre-rRNAs and U3 snoRNA.<ref>PMID:7744014</ref> <ref>PMID:10747033</ref> <ref>PMID:10761922</ref> <ref>PMID:12077351</ref> <ref>PMID:12438310</ref> <ref>PMID:15485930</ref> 


Authors: Sharif, H., Conti, E.
==About this Structure==
[[4c92]] is a 7 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae] and [http://en.wikipedia.org/wiki/Zasmidium_angulare Zasmidium angulare]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4C92 OCA].  


Description: Crystal structure of the yeast Lsm1-7 complex
==Reference==
<references group="xtra"/><references/>
[[Category: Saccharomyces cerevisiae]]
[[Category: Zasmidium angulare]]
[[Category: Conti, E.]]
[[Category: Sharif, H.]]
[[Category: Decapping activator]]
[[Category: Lsm1-7]]
[[Category: Mrna degradation]]
[[Category: Transcription]]