2ou7: Difference between revisions

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[[Image:2ou7.gif|left|200px]]<br /><applet load="2ou7" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2ou7.gif|left|200px]]
caption="2ou7, resolution 2.40&Aring;" />
 
'''Structure of the Catalytic Domain of Human Polo-like Kinase 1'''<br />
{{Structure
|PDB= 2ou7 |SIZE=350|CAPTION= <scene name='initialview01'>2ou7</scene>, resolution 2.40&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene> and <scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER'>ANP</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Polo_kinase Polo kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.21 2.7.11.21]
|GENE= PLK1, PLK ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''Structure of the Catalytic Domain of Human Polo-like Kinase 1'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2OU7 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=ZN:'>ZN</scene>, <scene name='pdbligand=ACT:'>ACT</scene>, <scene name='pdbligand=MG:'>MG</scene> and <scene name='pdbligand=ANP:'>ANP</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Polo_kinase Polo kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.21 2.7.11.21] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OU7 OCA].  
2OU7 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OU7 OCA].  


==Reference==
==Reference==
Structure of the catalytic domain of human polo-like kinase 1., Kothe M, Kohls D, Low S, Coli R, Cheng AC, Jacques SL, Johnson TL, Lewis C, Loh C, Nonomiya J, Sheils AL, Verdries KA, Wynn TA, Kuhn C, Ding YH, Biochemistry. 2007 May 22;46(20):5960-71. Epub 2007 Apr 27. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17461553 17461553]
Structure of the catalytic domain of human polo-like kinase 1., Kothe M, Kohls D, Low S, Coli R, Cheng AC, Jacques SL, Johnson TL, Lewis C, Loh C, Nonomiya J, Sheils AL, Verdries KA, Wynn TA, Kuhn C, Ding YH, Biochemistry. 2007 May 22;46(20):5960-71. Epub 2007 Apr 27. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17461553 17461553]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Polo kinase]]
[[Category: Polo kinase]]
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[[Category: kinase domain]]
[[Category: kinase domain]]


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