4mze: Difference between revisions
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{{STRUCTURE_4mze| PDB=4mze | SCENE= }} | |||
===Crystal structure of hPIV3 hemagglutinin-neuraminidase, H552Q/Q559R mutant=== | |||
{{ABSTRACT_PUBMED_24149514}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/HN_PI3H4 HN_PI3H4]] Attaches the virus to sialic acid-containing cell receptors and thereby initiating infection. Binding of HN protein to the receptor induces a conformational change that allows the F protein to trigger virion/cell membranes fusion (By similarity). Neuraminidase activity ensures the efficient spread of the virus by dissociating the mature virions from the neuraminic acid containing glycoproteins (By similarity). | |||
==About this Structure== | |||
[[4mze]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_parainfluenza_3_virus_(strain_nih_47885) Human parainfluenza 3 virus (strain nih 47885)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MZE OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:024149514</ref><references group="xtra"/><references/> | |||
[[Category: Exo-alpha-sialidase]] | |||
[[Category: Wilson, I A.]] | |||
[[Category: Xu, R.]] | |||
[[Category: Hydrolase]] | |||
[[Category: Viral envelope protein]] | |||
[[Category: Viral fusion protein]] | |||
