2ouh: Difference between revisions

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[[Image:2ouh.jpg|left|200px]]<br /><applet load="2ouh" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2ouh.jpg|left|200px]]
caption="2ouh, resolution 2.4&Aring;" />
 
'''Crystal structure of the Thrombospondin-1 N-terminal domain in complex with fractionated Heparin DP10'''<br />
{{Structure
|PDB= 2ouh |SIZE=350|CAPTION= <scene name='initialview01'>2ouh</scene>, resolution 2.4&Aring;
|SITE= <scene name='pdbsite=AC1:So4+Binding+Site+For+Residue+A+248'>AC1</scene>, <scene name='pdbsite=AC2:So4+Binding+Site+For+Residue+A+249'>AC2</scene>, <scene name='pdbsite=AC3:So4+Binding+Site+For+Residue+A+250'>AC3</scene>, <scene name='pdbsite=AC4:So4+Binding+Site+For+Residue+B+248'>AC4</scene>, <scene name='pdbsite=AC5:So4+Binding+Site+For+Residue+B+249'>AC5</scene> and <scene name='pdbsite=AC6:So4+Binding+Site+For+Residue+B+250'>AC6</scene>
|LIGAND= <scene name='pdbligand=SO4:SULFATE ION'>SO4</scene>
|ACTIVITY=
|GENE= THBS1, TSP, TSP1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''Crystal structure of the Thrombospondin-1 N-terminal domain in complex with fractionated Heparin DP10'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2OUH is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=SO4:'>SO4</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Known structural/functional Sites: <scene name='pdbsite=AC1:So4+Binding+Site+For+Residue+A+248'>AC1</scene>, <scene name='pdbsite=AC2:So4+Binding+Site+For+Residue+A+249'>AC2</scene>, <scene name='pdbsite=AC3:So4+Binding+Site+For+Residue+A+250'>AC3</scene>, <scene name='pdbsite=AC4:So4+Binding+Site+For+Residue+B+248'>AC4</scene>, <scene name='pdbsite=AC5:So4+Binding+Site+For+Residue+B+249'>AC5</scene> and <scene name='pdbsite=AC6:So4+Binding+Site+For+Residue+B+250'>AC6</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OUH OCA].  
2OUH is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OUH OCA].  


==Reference==
==Reference==
Heparin-induced cis- and trans-Dimerization Modes of the Thrombospondin-1 N-terminal Domain., Tan K, Duquette M, Liu JH, Shanmugasundaram K, Joachimiak A, Gallagher JT, Rigby AC, Wang JH, Lawler J, J Biol Chem. 2008 Feb 15;283(7):3932-41. Epub 2007 Dec 7. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=18065761 18065761]
Heparin-induced cis- and trans-Dimerization Modes of the Thrombospondin-1 N-terminal Domain., Tan K, Duquette M, Liu JH, Shanmugasundaram K, Joachimiak A, Gallagher JT, Rigby AC, Wang JH, Lawler J, J Biol Chem. 2008 Feb 15;283(7):3932-41. Epub 2007 Dec 7. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18065761 18065761]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: tspn-1]]
[[Category: tspn-1]]


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