2oxw: Difference between revisions
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[[Image:2oxw.jpg|left|200px]] | [[Image:2oxw.jpg|left|200px]] | ||
'''Human MMP-12 complexed with the peptide IAG''' | {{Structure | ||
|PDB= 2oxw |SIZE=350|CAPTION= <scene name='initialview01'>2oxw</scene>, resolution 1.15Å | |||
|SITE= | |||
|LIGAND= <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene> and <scene name='pdbligand=CA:CALCIUM ION'>CA</scene> | |||
|ACTIVITY= [http://en.wikipedia.org/wiki/Macrophage_elastase Macrophage elastase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.65 3.4.24.65] | |||
|GENE= MMP12, HME ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]) | |||
}} | |||
'''Human MMP-12 complexed with the peptide IAG''' | |||
==Disease== | ==Disease== | ||
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==About this Structure== | ==About this Structure== | ||
2OXW is a [ | 2OXW is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OXW OCA]. | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Macrophage elastase]] | [[Category: Macrophage elastase]] | ||
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[[Category: mmp-12]] | [[Category: mmp-12]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 18:06:05 2008'' | ||
Revision as of 16:06, 20 March 2008
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| 2oxw, resolution 1.15Å | |||||||||||||
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| Ligands: | ZN and CA | ||||||||||||
| Gene: | MMP12, HME (Homo sapiens) | ||||||||||||
| Activity: | Macrophage elastase, with EC number 3.4.24.65 | ||||||||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||||||||
Human MMP-12 complexed with the peptide IAG
Disease
Known diseases associated with this structure: Cardiomyopathy, dilated, 1G OMIM:[188840], Cardiomyopathy, familial hypertrophic OMIM:[188840], Muscular dystrophy, limb-girdle, type 2J OMIM:[188840], Myopathy, early-onset, with fatal cardiomyopathy OMIM:[188840], Myopathy, proximal, with early respiratory muscle involvement OMIM:[188840], Tibial muscular dystrophy, tardive OMIM:[188840]
About this Structure
2OXW is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Page seeded by OCA on Thu Mar 20 18:06:05 2008
