2oz5: Difference between revisions

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[[Image:2oz5.gif|left|200px]]<br /><applet load="2oz5" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2oz5.gif|left|200px]]
caption="2oz5, resolution 2.000&Aring;" />
 
'''Crystal structure of Mycobacterium tuberculosis protein tyrosine phosphatase PtpB in complex with the specific inhibitor OMTS'''<br />
{{Structure
|PDB= 2oz5 |SIZE=350|CAPTION= <scene name='initialview01'>2oz5</scene>, resolution 2.000&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=7XY:{(3-CHLOROBENZYL)[(5-{[(3,3-DIPHENYLPROPYL)AMINO]SULFONYL}-2-THIENYL)METHYL]AMINO}(OXO)ACETIC ACID'>7XY</scene>
|ACTIVITY=
|GENE= ptpB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 Mycobacterium tuberculosis])
}}
 
'''Crystal structure of Mycobacterium tuberculosis protein tyrosine phosphatase PtpB in complex with the specific inhibitor OMTS'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2OZ5 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis] with <scene name='pdbligand=7XY:'>7XY</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OZ5 OCA].  
2OZ5 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OZ5 OCA].  


==Reference==
==Reference==
Structural basis for selective inhibition of Mycobacterium tuberculosis protein tyrosine phosphatase PtpB., Grundner C, Perrin D, Hooft van Huijsduijnen R, Swinnen D, Gonzalez J, Gee CL, Wells TN, Alber T, Structure. 2007 Apr;15(4):499-509. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17437721 17437721]
Structural basis for selective inhibition of Mycobacterium tuberculosis protein tyrosine phosphatase PtpB., Grundner C, Perrin D, Hooft van Huijsduijnen R, Swinnen D, Gonzalez J, Gee CL, Wells TN, Alber T, Structure. 2007 Apr;15(4):499-509. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17437721 17437721]
[[Category: Mycobacterium tuberculosis]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: 7XY]]
[[Category: 7XY]]
[[Category: protein tyrosine phosphatase in complex with small molecule inhibitor]]
[[Category: protein tyrosine phosphatase in complex with small molecule inhibitor]]
[[Category: structural genomics]]
[[Category: structural genomic]]
[[Category: tb structural genomics consortium]]
[[Category: tb structural genomics consortium]]
[[Category: tbsgc]]
[[Category: tbsgc]]


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