3wix: Difference between revisions
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{{STRUCTURE_3wix| PDB=3wix | SCENE= }} | |||
===Crystal structure of Mcl-1 in complex with compound 4=== | |||
{{ABSTRACT_PUBMED_24215352}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/MCL1_HUMAN MCL1_HUMAN]] Involved in the regulation of apoptosis versus cell survival, and in the maintenance of viability but not of proliferation. Mediates its effects by interactions with a number of other regulators of apoptosis. Isoform 1 inhibits apoptosis. Isoform 2 promotes apoptosis.<ref>PMID:10766760</ref> | |||
==About this Structure== | |||
[[3wix]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WIX OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:024215352</ref><references group="xtra"/><references/> | |||
[[Category: Hayano, Y.]] | |||
[[Category: Igaki, S.]] | |||
[[Category: Sogabe, S.]] | |||
[[Category: Apoptosis]] | |||
[[Category: Regulation]] | |||