2p15: Difference between revisions

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[[Image:2p15.gif|left|200px]]~~<br /><applet load~~="2p15~~" size~~="350~~" color~~=~~"white" frame~~=~~"true" align="right" spinBox="true"~~

[[Image:2p15.gif|left|200px]]

~~caption="~~2p15, resolution 1.940Å" />

'''Crystal structure of the ER alpha ligand binding domain with the agonist ortho-trifluoromethylphenylvinyl estradiol'''~~<br />~~

{{Structure

|PDB= 2p15 |SIZE=350|CAPTION= <scene name='initialview01'>2p15</scene>, resolution 1.940Å

|SITE=

|LIGAND= <scene name='pdbligand=EZT:(17BETA)-17-{(E)-2-[2-(TRIFLUOROMETHYL)PHENYL]VINYL}ESTRA-1(10),2,4-TRIENE-3,17-DIOL'>EZT</scene>

|ACTIVITY=

|GENE= ESR1, ESR, NR3A1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])

}}

'''Crystal structure of the ER alpha ligand binding domain with the agonist ortho-trifluoromethylphenylvinyl estradiol'''

==Overview==

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==About this Structure==

2P15 is a [~~http://en.wikipedia.org/wiki/Protein_complex~~ Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens~~] with <scene name='pdbligand=EZT:'>EZT</scene> as [http://en.wikipedia.org/wiki/ligand ligand~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P15 OCA].

2P15 is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P15 OCA].

==Reference==

Structural plasticity in the oestrogen receptor ligand-binding domain., Nettles KW, Bruning JB, Gil G, O'Neill EE, Nowak J, Guo Y, Kim Y, DeSombre ER, Dilis R, Hanson RN, Joachimiak A, Greene GL, EMBO Rep. 2007 Jun;8(6):563-8. Epub 2007 Apr 27. PMID:[http://~~ispc~~.~~weizmann~~.ac.~~il/~~/~~pmbin~~/~~getpm?pmid=~~17468738 17468738]

Structural plasticity in the oestrogen receptor ligand-binding domain., Nettles KW, Bruning JB, Gil G, O'Neill EE, Nowak J, Guo Y, Kim Y, DeSombre ER, Dilis R, Hanson RN, Joachimiak A, Greene GL, EMBO Rep. 2007 Jun;8(6):563-8. Epub 2007 Apr 27. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17468738 17468738]

[[Category: Homo sapiens]]

[[Category: Protein complex]]

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[[Category: nulear receptor]]

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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 18:07:11 2008''

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@@ Line 1: / Line 1: @@
-[[Image:2p15.gif|left|200px]]<br /><applet load="2p15" size="350" color="white" frame="true" align="right" spinBox="true"
+[[Image:2p15.gif|left|200px]]
-caption="2p15, resolution 1.940&Aring;" />
-'''Crystal structure of the ER alpha ligand binding domain with the agonist ortho-trifluoromethylphenylvinyl estradiol'''<br />
+ {{Structure
+|PDB= 2p15 |SIZE=350|CAPTION= <scene name='initialview01'>2p15</scene>, resolution 1.940&Aring;
+|SITE=
+|LIGAND= <scene name='pdbligand=EZT:(17BETA)-17-{(E)-2-[2-(TRIFLUOROMETHYL)PHENYL]VINYL}ESTRA-1(10),2,4-TRIENE-3,17-DIOL'>EZT</scene>
+|ACTIVITY=
+|GENE= ESR1, ESR, NR3A1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
+}}
+'''Crystal structure of the ER alpha ligand binding domain with the agonist ortho-trifluoromethylphenylvinyl estradiol'''
 ==Overview==
@@ Line 10: / Line 19: @@
 ==About this Structure==
-P15 is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=EZT:'>EZT</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P15 OCA].
+P15 is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P15 OCA].
 ==Reference==
-Structural plasticity in the oestrogen receptor ligand-binding domain., Nettles KW, Bruning JB, Gil G, O'Neill EE, Nowak J, Guo Y, Kim Y, DeSombre ER, Dilis R, Hanson RN, Joachimiak A, Greene GL, EMBO Rep. 2007 Jun;8(6):563-8. Epub 2007 Apr 27. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17468738 17468738]
+Structural plasticity in the oestrogen receptor ligand-binding domain., Nettles KW, Bruning JB, Gil G, O'Neill EE, Nowak J, Guo Y, Kim Y, DeSombre ER, Dilis R, Hanson RN, Joachimiak A, Greene GL, EMBO Rep. 2007 Jun;8(6):563-8. Epub 2007 Apr 27. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17468738 17468738]
 [[Category: Homo sapiens]]
 [[Category: Protein complex]]
@@ Line 25: / Line 34: @@
 [[Category: nulear receptor]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 18:24:43 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 18:07:11 2008''