2p1u: Difference between revisions

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[[Image:2p1u.jpg|left|200px]]<br /><applet load="2p1u" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2p1u.jpg|left|200px]]
caption="2p1u, resolution 2.200&Aring;" />
 
'''Crystal structure of the ligand binding domain of the retinoid X receptor alpha in complex with 3-(2'-ethoxy)-tetrahydronaphtyl cinnamic acid and a fragment of the coactivator TIF-2'''<br />
{{Structure
|PDB= 2p1u |SIZE=350|CAPTION= <scene name='initialview01'>2p1u</scene>, resolution 2.200&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=4TN:(2E)-3-[3-(3-ETHOXY-5,5,8,8-TETRAMETHYL-5,6,7,8-TETRAHYDRONAPHTHALEN-2-YL)-4-HYDROXYPHENYL]ACRYLIC ACID'>4TN</scene>
|ACTIVITY=
|GENE= RXRA, NR2B1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''Crystal structure of the ligand binding domain of the retinoid X receptor alpha in complex with 3-(2'-ethoxy)-tetrahydronaphtyl cinnamic acid and a fragment of the coactivator TIF-2'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2P1U is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=4TN:'>4TN</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P1U OCA].  
2P1U is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P1U OCA].  


==Reference==
==Reference==
Modulators of the structural dynamics of the retinoid X receptor to reveal receptor function., Nahoum V, Perez E, Germain P, Rodriguez-Barrios F, Manzo F, Kammerer S, Lemaire G, Hirsch O, Royer CA, Gronemeyer H, de Lera AR, Bourguet W, Proc Natl Acad Sci U S A. 2007 Oct 30;104(44):17323-8. Epub 2007 Oct 18. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17947383 17947383]
Modulators of the structural dynamics of the retinoid X receptor to reveal receptor function., Nahoum V, Perez E, Germain P, Rodriguez-Barrios F, Manzo F, Kammerer S, Lemaire G, Hirsch O, Royer CA, Gronemeyer H, de Lera AR, Bourguet W, Proc Natl Acad Sci U S A. 2007 Oct 30;104(44):17323-8. Epub 2007 Oct 18. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17947383 17947383]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Protein complex]]
[[Category: Protein complex]]
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[[Category: protein-ligand complex]]
[[Category: protein-ligand complex]]


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