2p2f: Difference between revisions

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[[Image:2p2f.jpg|left|200px]]<br /><applet load="2p2f" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2p2f.jpg|left|200px]]
caption="2p2f, resolution 2.580&Aring;" />
 
'''Acetyl-CoA Synthetase, wild-type with acetate, AMP, and CoA bound'''<br />
{{Structure
|PDB= 2p2f |SIZE=350|CAPTION= <scene name='initialview01'>2p2f</scene>, resolution 2.580&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=COA:COENZYME+A'>COA</scene> and <scene name='pdbligand=AMP:ADENOSINE MONOPHOSPHATE'>AMP</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Acetate--CoA_ligase Acetate--CoA ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.2.1.1 6.2.1.1]
|GENE= acs ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=602 Salmonella typhimurium])
}}
 
'''Acetyl-CoA Synthetase, wild-type with acetate, AMP, and CoA bound'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2P2F is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Salmonella_typhimurium Salmonella typhimurium] with <scene name='pdbligand=ACT:'>ACT</scene>, <scene name='pdbligand=COA:'>COA</scene> and <scene name='pdbligand=AMP:'>AMP</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Acetate--CoA_ligase Acetate--CoA ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.2.1.1 6.2.1.1] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P2F OCA].  
2P2F is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Salmonella_typhimurium Salmonella typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P2F OCA].  


==Reference==
==Reference==
Biochemical and crystallographic analysis of substrate binding and conformational changes in acetyl-CoA synthetase., Reger AS, Carney JM, Gulick AM, Biochemistry. 2007 Jun 5;46(22):6536-46. Epub 2007 May 12. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17497934 17497934]
Biochemical and crystallographic analysis of substrate binding and conformational changes in acetyl-CoA synthetase., Reger AS, Carney JM, Gulick AM, Biochemistry. 2007 Jun 5;46(22):6536-46. Epub 2007 May 12. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17497934 17497934]
[[Category: Acetate--CoA ligase]]
[[Category: Acetate--CoA ligase]]
[[Category: Salmonella typhimurium]]
[[Category: Salmonella typhimurium]]
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[[Category: COA]]
[[Category: COA]]
[[Category: acyl-coa ligase]]
[[Category: acyl-coa ligase]]
[[Category: adenylate-forming enzymes]]
[[Category: adenylate-forming enzyme]]
[[Category: domain alternation]]
[[Category: domain alternation]]


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