2p4s: Difference between revisions

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[[Image:2p4s.jpg|left|200px]]<br /><applet load="2p4s" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2p4s.jpg|left|200px]]
caption="2p4s, resolution 2.20&Aring;" />
 
'''Structure of Purine Nucleoside Phosphorylase from Anopheles gambiae in complex with DADMe-ImmH'''<br />
{{Structure
|PDB= 2p4s |SIZE=350|CAPTION= <scene name='initialview01'>2p4s</scene>, resolution 2.20&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene> and <scene name='pdbligand=DIH:3-HYDROXY-4-HYDROXYMETHYL-1-(4-OXO-4,4A,5,7A-TETRAHYDRO-3H-PYRROLO[3,2-D]PYRIMIDIN-7-YLMETHYL)-PYRROLIDINIUM'>DIH</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Purine-nucleoside_phosphorylase Purine-nucleoside phosphorylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.1 2.4.2.1]
|GENE= pnp ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7165 Anopheles gambiae])
}}
 
'''Structure of Purine Nucleoside Phosphorylase from Anopheles gambiae in complex with DADMe-ImmH'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2P4S is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Anopheles_gambiae Anopheles gambiae] with <scene name='pdbligand=PO4:'>PO4</scene> and <scene name='pdbligand=DIH:'>DIH</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Purine-nucleoside_phosphorylase Purine-nucleoside phosphorylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.1 2.4.2.1] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P4S OCA].  
2P4S is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Anopheles_gambiae Anopheles gambiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P4S OCA].  


==Reference==
==Reference==
Anopheles gambiae purine nucleoside phosphorylase: catalysis, structure, and inhibition., Taylor EA, Rinaldo-Matthis A, Li L, Ghanem M, Hazleton KZ, Cassera MB, Almo SC, Schramm VL, Biochemistry. 2007 Oct 30;46(43):12405-15. Epub 2007 Oct 6. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17918964 17918964]
Anopheles gambiae purine nucleoside phosphorylase: catalysis, structure, and inhibition., Taylor EA, Rinaldo-Matthis A, Li L, Ghanem M, Hazleton KZ, Cassera MB, Almo SC, Schramm VL, Biochemistry. 2007 Oct 30;46(43):12405-15. Epub 2007 Oct 6. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17918964 17918964]
[[Category: Anopheles gambiae]]
[[Category: Anopheles gambiae]]
[[Category: Purine-nucleoside phosphorylase]]
[[Category: Purine-nucleoside phosphorylase]]
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[[Category: transferase]]
[[Category: transferase]]


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