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{{STRUCTURE_4ky0|  PDB=4ky0  |  SCENE=  }}
==Crystal structure of a substrate-free glutamate transporter homologue from Thermococcus kodakarensis==
===Crystal structure of a substrate-free glutamate transporter homologue from Thermococcus kodakarensis===
<StructureSection load='4ky0' size='340' side='right' caption='[[4ky0]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
{{ABSTRACT_PUBMED_24013209}}
== Structural highlights ==
<table><tr><td colspan='2'>[[4ky0]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermococcus_kodakarensis_kod1 Thermococcus kodakarensis kod1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KY0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4KY0 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TK0986 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=69014 Thermococcus kodakarensis KOD1])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ky0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ky0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ky0 RCSB], [http://www.ebi.ac.uk/pdbsum/4ky0 PDBsum]</span></td></tr>
</table>
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
Archaeal glutamate transporter homologs catalyze the coupled uptake of aspartate and three sodium ions. After the delivery of the substrate and sodium ions to the cytoplasm, the empty binding site must reorient to the outward-facing conformation to reset the transporter. Here, we report a crystal structure of the substrate-free transporter GltTk from Thermococcus kodakarensis, which provides insight into the mechanism of this essential step in the translocation cycle.


==About this Structure==
Crystal structure of a substrate-free aspartate transporter.,Jensen S, Guskov A, Rempel S, Hanelt I, Slotboom DJ Nat Struct Mol Biol. 2013 Oct;20(10):1224-6. doi: 10.1038/nsmb.2663. Epub 2013, Sep 8. PMID:24013209<ref>PMID:24013209</ref>
[[4ky0]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermococcus_kodakarensis_kod1 Thermococcus kodakarensis kod1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KY0 OCA].


==Reference==
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
<ref group="xtra">PMID:024013209</ref><references group="xtra"/><references/>
</div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Thermococcus kodakarensis kod1]]
[[Category: Thermococcus kodakarensis kod1]]
[[Category: Guskov, A.]]
[[Category: Guskov, A]]
[[Category: Hanelt, I.]]
[[Category: Hanelt, I]]
[[Category: Jensen, S.]]
[[Category: Jensen, S]]
[[Category: Rempel, S.]]
[[Category: Rempel, S]]
[[Category: Slotboom, D J.]]
[[Category: Slotboom, D J]]
[[Category: Amino acid transporter]]
[[Category: Amino acid transporter]]
[[Category: Aspartate transport]]
[[Category: Aspartate transport]]
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