4mpm: Difference between revisions

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'''Unreleased structure'''
{{STRUCTURE_4mpm|  PDB=4mpm  |  SCENE=  }}
===Wild-type human neuroglobin===


The entry 4mpm is ON HOLD until Paper Publication
==Function==
[[http://www.uniprot.org/uniprot/NGB_HUMAN NGB_HUMAN]] Involved in oxygen transport in the brain. Hexacoordinate globin, displaying competitive binding of oxygen or the distal His residue to the iron atom. Not capable of penetrating cell membranes. The deoxygenated form exhibits nitrite reductase activity inhibiting cellular respiration via NO-binding to cytochrome c oxidase. Involved in neuroprotection during oxidative stress. May exert its anti-apoptotic activity by acting to reset the trigger level of mitochondrial cytochrome c release necessary to commit the cells to apoptosis.<ref>PMID:11029004</ref> <ref>PMID:11473128</ref> <ref>PMID:18416560</ref> <ref>PMID:21190290</ref> <ref>PMID:21296891</ref>  


Authors: Guimaraes, B.G., Golinelli-Pimpaneau, B.
==About this Structure==
[[4mpm]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MPM OCA].  


Description: Wild-type human neuroglobin
==Reference==
<references group="xtra"/><references/>
[[Category: Golinelli-Pimpaneau, B.]]
[[Category: Guimaraes, B G.]]
[[Category: Apoptosis]]
[[Category: Brain neuron]]
[[Category: Globin]]
[[Category: Nitrite reductase]]
[[Category: Oxygen supply]]
[[Category: Proto-porphyrin ix]]
Retrieved from "https://proteopedia.org/4mpm"