2pax: Difference between revisions

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[[Image:2pax.jpg|left|200px]]<br /><applet load="2pax" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2pax.jpg|left|200px]]
caption="2pax, resolution 2.4&Aring;" />
 
'''THE CATALYTIC FRAGMENT OF POLY(ADP-RIBOSE) POLYMERASE COMPLEXED WITH 4-AMINO-1,8-NAPHTHALIMIDE'''<br />
{{Structure
|PDB= 2pax |SIZE=350|CAPTION= <scene name='initialview01'>2pax</scene>, resolution 2.4&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=4AN:6-AMINO-BENZO[DE]ISOQUINOLINE-1,3-DIONE'>4AN</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/NAD(+)_ADP-ribosyltransferase NAD(+) ADP-ribosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.30 2.4.2.30]
|GENE=
}}
 
'''THE CATALYTIC FRAGMENT OF POLY(ADP-RIBOSE) POLYMERASE COMPLEXED WITH 4-AMINO-1,8-NAPHTHALIMIDE'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2PAX is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus] with <scene name='pdbligand=4AN:'>4AN</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/NAD(+)_ADP-ribosyltransferase NAD(+) ADP-ribosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.30 2.4.2.30] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PAX OCA].  
2PAX is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PAX OCA].  


==Reference==
==Reference==
Inhibitor and NAD+ binding to poly(ADP-ribose) polymerase as derived from crystal structures and homology modeling., Ruf A, de Murcia G, Schulz GE, Biochemistry. 1998 Mar 17;37(11):3893-900. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9521710 9521710]
Inhibitor and NAD+ binding to poly(ADP-ribose) polymerase as derived from crystal structures and homology modeling., Ruf A, de Murcia G, Schulz GE, Biochemistry. 1998 Mar 17;37(11):3893-900. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9521710 9521710]
[[Category: Gallus gallus]]
[[Category: Gallus gallus]]
[[Category: NAD(+) ADP-ribosyltransferase]]
[[Category: NAD(+) ADP-ribosyltransferase]]
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[[Category: transferase]]
[[Category: transferase]]


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