2pb1: Difference between revisions

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[[Image:2pb1.gif|left|200px]]<br /><applet load="2pb1" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2pb1.gif|left|200px]]
caption="2pb1, resolution 1.900&Aring;" />
 
'''Exo-B-(1,3)-Glucanase from Candida Albicans in complex with unhydrolysed and covalently linked 2,4-dinitrophenyl-2-deoxy-2-fluoro-B-D-glucopyranoside at 1.9 A'''<br />
{{Structure
|PDB= 2pb1 |SIZE=350|CAPTION= <scene name='initialview01'>2pb1</scene>, resolution 1.900&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=G2F:2-DEOXY-2FLUORO-GLUCOSE'>G2F</scene> and <scene name='pdbligand=NFG:2,4-DINITROPHENYL 2-DEOXY-2-FLUORO-BETA-D-GLUCOPYRANOSIDE'>NFG</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Glucan_1,3-beta-glucosidase Glucan 1,3-beta-glucosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.58 3.2.1.58]
|GENE= EXG ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5476 Candida albicans])
}}
 
'''Exo-B-(1,3)-Glucanase from Candida Albicans in complex with unhydrolysed and covalently linked 2,4-dinitrophenyl-2-deoxy-2-fluoro-B-D-glucopyranoside at 1.9 A'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2PB1 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Candida_albicans Candida albicans] with <scene name='pdbligand=G2F:'>G2F</scene> and <scene name='pdbligand=NFG:'>NFG</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Glucan_1,3-beta-glucosidase Glucan 1,3-beta-glucosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.58 3.2.1.58] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PB1 OCA].  
2PB1 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Candida_albicans Candida albicans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PB1 OCA].  


==Reference==
==Reference==
The structure of the exo-beta-(1,3)-glucanase from Candida albicans in native and bound forms: relationship between a pocket and groove in family 5 glycosyl hydrolases., Cutfield SM, Davies GJ, Murshudov G, Anderson BF, Moody PC, Sullivan PA, Cutfield JF, J Mol Biol. 1999 Dec 3;294(3):771-83. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=10610795 10610795]
The structure of the exo-beta-(1,3)-glucanase from Candida albicans in native and bound forms: relationship between a pocket and groove in family 5 glycosyl hydrolases., Cutfield SM, Davies GJ, Murshudov G, Anderson BF, Moody PC, Sullivan PA, Cutfield JF, J Mol Biol. 1999 Dec 3;294(3):771-83. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10610795 10610795]
[[Category: Candida albicans]]
[[Category: Candida albicans]]
[[Category: Glucan 1,3-beta-glucosidase]]
[[Category: Glucan 1,3-beta-glucosidase]]
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[[Category: G2F]]
[[Category: G2F]]
[[Category: NFG]]
[[Category: NFG]]
[[Category: candida albicans]]
[[Category: candida albican]]
[[Category: exo-glucanase]]
[[Category: exo-glucanase]]
[[Category: mechanism-based inhibitor]]
[[Category: mechanism-based inhibitor]]


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