2pgj: Difference between revisions

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[[Image:2pgj.gif|left|200px]]<br /><applet load="2pgj" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2pgj.gif|left|200px]]
caption="2pgj, resolution 1.71&Aring;" />
 
'''Catalysis associated conformational changes revealed by human cd38 complexed with a non-hydrolyzable substrate analog'''<br />
{{Structure
|PDB= 2pgj |SIZE=350|CAPTION= <scene name='initialview01'>2pgj</scene>, resolution 1.71&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=N1C:N1-CYCLIC INOSINE 5'-DIPHOSPHORIBOSE'>N1C</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/NAD(+)_nucleosidase NAD(+) nucleosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.5 3.2.2.5]
|GENE= CD38 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''Catalysis associated conformational changes revealed by human cd38 complexed with a non-hydrolyzable substrate analog'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2PGJ is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=N1C:'>N1C</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/NAD(+)_nucleosidase NAD(+) nucleosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.5 3.2.2.5] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PGJ OCA].  
2PGJ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PGJ OCA].  


==Reference==
==Reference==
Catalysis-associated conformational changes revealed by human CD38 complexed with a non-hydrolyzable substrate analog., Liu Q, Kriksunov IA, Moreau C, Graeff R, Potter BV, Lee HC, Hao Q, J Biol Chem. 2007 Aug 24;282(34):24825-32. Epub 2007 Jun 25. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17591784 17591784]
Catalysis-associated conformational changes revealed by human CD38 complexed with a non-hydrolyzable substrate analog., Liu Q, Kriksunov IA, Moreau C, Graeff R, Potter BV, Lee HC, Hao Q, J Biol Chem. 2007 Aug 24;282(34):24825-32. Epub 2007 Jun 25. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17591784 17591784]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: NAD(+) nucleosidase]]
[[Category: NAD(+) nucleosidase]]
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[[Category: wild-type cd38 bound with n1-cidpr]]
[[Category: wild-type cd38 bound with n1-cidpr]]


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