2pip: Difference between revisions
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[[Image:2pip.jpg|left|200px]] | [[Image:2pip.jpg|left|200px]] | ||
'''Androgen receptor LBD with small molecule''' | {{Structure | ||
|PDB= 2pip |SIZE=350|CAPTION= <scene name='initialview01'>2pip</scene>, resolution 1.8Å | |||
|SITE= | |||
|LIGAND= <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=DHT:DIHYDROTESTOSTERONE'>DHT</scene>, <scene name='pdbligand=ICO:1H-INDOLE-3-CARBOXYLIC+ACID'>ICO</scene> and <scene name='pdbligand=K10:1-TERT-BUTYL-3-(2,5-DIMETHYLBENZYL)-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-AMINE'>K10</scene> | |||
|ACTIVITY= | |||
|GENE= AR, DHTR, NR3C4 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]) | |||
}} | |||
'''Androgen receptor LBD with small molecule''' | |||
==Disease== | ==Disease== | ||
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==About this Structure== | ==About this Structure== | ||
2PIP is a [ | 2PIP is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PIP OCA]. | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
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[[Category: af-2 pocket]] | [[Category: af-2 pocket]] | ||
[[Category: androgen receptor]] | [[Category: androgen receptor]] | ||
[[Category: | [[Category: coactivator]] | ||
[[Category: hormone receptor]] | [[Category: hormone receptor]] | ||
[[Category: | [[Category: inhibitor]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 18:13:28 2008'' | ||
Revision as of 16:13, 20 March 2008
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| 2pip, resolution 1.8Å | |||||||||||||
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| Ligands: | SO4, DHT, ICO and K10 | ||||||||||||
| Gene: | AR, DHTR, NR3C4 (Homo sapiens) | ||||||||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||||||||
Androgen receptor LBD with small molecule
Disease
Known diseases associated with this structure: Androgen insensitivity OMIM:[313700], Breast cancer, male, with Reifenstein syndrome OMIM:[313700], Hypospadias, perineal OMIM:[313700], Prostate cancer OMIM:[313700], Prostate cancer, susceptibility to OMIM:[313700], Spinal and bulbar muscular atrophy of Kennedy OMIM:[313700]
About this Structure
2PIP is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Page seeded by OCA on Thu Mar 20 18:13:28 2008
