2pkm: Difference between revisions

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[[Image:2pkm.jpg|left|200px]]<br /><applet load="2pkm" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2pkm.jpg|left|200px]]
caption="2pkm, resolution 1.90&Aring;" />
 
'''Crystal structure of M tuberculosis Adenosine Kinase complexed with adenosine'''<br />
{{Structure
|PDB= 2pkm |SIZE=350|CAPTION= <scene name='initialview01'>2pkm</scene>, resolution 1.90&Aring;
|SITE= <scene name='pdbsite=AC1:Adn+Binding+Site+For+Residue+A+501'>AC1</scene>
|LIGAND= <scene name='pdbligand=ADN:ADENOSINE'>ADN</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Adenosine_kinase Adenosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.20 2.7.1.20]
|GENE= Rv2202 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 Mycobacterium tuberculosis])
}}
 
'''Crystal structure of M tuberculosis Adenosine Kinase complexed with adenosine'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2PKM is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis] with <scene name='pdbligand=ADN:'>ADN</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Adenosine_kinase Adenosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.20 2.7.1.20] Known structural/functional Site: <scene name='pdbsite=AC1:Adn+Binding+Site+For+Residue+A+501'>AC1</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PKM OCA].  
2PKM is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PKM OCA].  


==Reference==
==Reference==
High resolution crystal structures of Mycobacterium tuberculosis adenosine kinase: insights into the mechanism and specificity of this novel prokaryotic enzyme., Reddy MC, Palaninathan SK, Shetty ND, Owen JL, Watson MD, Sacchettini JC, J Biol Chem. 2007 Sep 14;282(37):27334-42. Epub 2007 Jun 26. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17597075 17597075]
High resolution crystal structures of Mycobacterium tuberculosis adenosine kinase: insights into the mechanism and specificity of this novel prokaryotic enzyme., Reddy MC, Palaninathan SK, Shetty ND, Owen JL, Watson MD, Sacchettini JC, J Biol Chem. 2007 Sep 14;282(37):27334-42. Epub 2007 Jun 26. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17597075 17597075]
[[Category: Adenosine kinase]]
[[Category: Adenosine kinase]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Mycobacterium tuberculosis]]
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[[Category: adenosine kinase]]
[[Category: adenosine kinase]]
[[Category: mycobacterium tuberculosis]]
[[Category: mycobacterium tuberculosis]]
[[Category: structural genomics]]
[[Category: structural genomic]]
[[Category: tb structural genomics consortium]]
[[Category: tb structural genomics consortium]]
[[Category: tbsgc]]
[[Category: tbsgc]]
[[Category: transferase]]
[[Category: transferase]]


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