4lmk: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
{{STRUCTURE_4lmk| PDB=4lmk | SCENE= }} | {{STRUCTURE_4lmk| PDB=4lmk | SCENE= }} | ||
===GLIC Liganded-closed-channel Conformation, Mutant Y27'A=== | ===GLIC Liganded-closed-channel Conformation, Mutant Y27'A=== | ||
{{ABSTRACT_PUBMED_24167270}} | |||
==Function== | ==Function== | ||
| Line 6: | Line 7: | ||
==About this Structure== | ==About this Structure== | ||
[[4lmk]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/ | [[4lmk]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Glovo Glovo]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LMK OCA]. | ||
==Reference== | ==Reference== | ||
<references group="xtra"/><references/> | <ref group="xtra">PMID:024167270</ref><references group="xtra"/><references/> | ||
[[Category: | [[Category: Glovo]] | ||
[[Category: Gonzalez-Gutierrez, G.]] | [[Category: Gonzalez-Gutierrez, G.]] | ||
[[Category: Grosman, C.]] | [[Category: Grosman, C.]] | ||
Revision as of 06:28, 13 November 2013
GLIC Liganded-closed-channel Conformation, Mutant Y27'A
Template:ABSTRACT PUBMED 24167270
Function
[GLIC_GLOVI] Cationic channel with similar permeabilities for Na(+) and K(+), that is activated by an increase of the proton concentration on the extracellular side. Displays no permeability for chloride ions. Shows slow kinetics of activation, no desensitization and a single channel conductance of 8 pS. Might contribute to adaptation to external pH change.[1]
About this Structure
4lmk is a 5 chain structure with sequence from Glovo. Full crystallographic information is available from OCA.
Reference
- Gonzalez-Gutierrez G, Cuello LG, Nair SK, Grosman C. Gating of the proton-gated ion channel from Gloeobacter violaceus at pH 4 as revealed by X-ray crystallography. Proc Natl Acad Sci U S A. 2013 Oct 28. PMID:24167270 doi:https://dx.doi.org/10.1073/pnas.1313156110
- ↑ Bocquet N, Prado de Carvalho L, Cartaud J, Neyton J, Le Poupon C, Taly A, Grutter T, Changeux JP, Corringer PJ. A prokaryotic proton-gated ion channel from the nicotinic acetylcholine receptor family. Nature. 2007 Jan 4;445(7123):116-9. Epub 2006 Dec 10. PMID:17167423 doi:10.1038/nature05371
