4m9i: Difference between revisions

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'''Unreleased structure'''
{{STRUCTURE_4m9i|  PDB=4m9i  |  SCENE=  }}
===A125C NS2B-NS3 protease from dengue virus at pH 5.5===
{{ABSTRACT_PUBMED_24164286}}


The entry 4m9i is ON HOLD  until Paper Publication
==Function==
[[http://www.uniprot.org/uniprot/Q91H74_9FLAV Q91H74_9FLAV]] Envelope protein E binding to host cell surface receptor is followed by virus internalization through clathrin-mediated endocytosis. Envelope protein E is subsequently involved in membrane fusion between virion and host late endosomes. Synthesized as a homodimer with prM which acts as a chaperone for envelope protein E. After cleavage of prM, envelope protein E dissociate from small envelope protein M and homodimerizes (By similarity).[SAAS:SAAS026470_004_099774]


Authors: Yildiz, M., Hardy, J.A.
==About this Structure==
[[4m9i]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M9I OCA].  


Description: A125C NS2B-NS3 protease from dengue virus at pH 5.5
==Reference==
<ref group="xtra">PMID:024164286</ref><references group="xtra"/><references/>
[[Category: Hardy, J A.]]
[[Category: Yildiz, M.]]
[[Category: Allosteric inhibition]]
[[Category: Conformational flexibility]]
[[Category: Dengue virus protease]]
[[Category: Serine protease]]
[[Category: Trypsin-like protease]]
[[Category: Viral protease]]
[[Category: Viral protein]]