4ime: Difference between revisions

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==About this Structure==
==About this Structure==
[[4ime]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Cylindrocarpon_theobromicola Cylindrocarpon theobromicola]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IME OCA].  
[[4ime]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Pasteurella_multocida_subsp._gallicida_p1059 Pasteurella multocida subsp. gallicida p1059]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IME OCA].  


==Reference==
==Reference==
<ref group="xtra">PMID:024152047</ref><references group="xtra"/><references/>
<ref group="xtra">PMID:024152047</ref><references group="xtra"/><references/>
[[Category: Cylindrocarpon theobromicola]]
[[Category: N-acetylneuraminate lyase]]
[[Category: N-acetylneuraminate lyase]]
[[Category: Pasteurella multocida subsp. gallicida p1059]]
[[Category: Fisher, A J.]]
[[Category: Fisher, A J.]]
[[Category: Huynh, N.]]
[[Category: Huynh, N.]]

Revision as of 12:29, 11 December 2013

Template:STRUCTURE 4ime

Crystal Structure of Pasteurella multocida N-Acetyl-D-Neuraminic acid lyase K164A Mutant

Template:ABSTRACT PUBMED 24152047

Function

[NANA_PASMU] Catalyzes the cleavage of N-acetylneuraminic acid (sialic acid) to form pyruvate and N-acetylmannosamine via a Schiff base intermediate (By similarity).

About this Structure

4ime is a 8 chain structure with sequence from Pasteurella multocida subsp. gallicida p1059. Full crystallographic information is available from OCA.

Reference

  1. Huynh N, Aye A, Li Y, Yu H, Cao H, Tiwari VK, Shin DW, Chen X, Fisher AJ. Structural basis for substrate specificity and mechanism of N-acetyl-D-neuraminic acid lyase from Pasteurella multocida. Biochemistry. 2013 Oct 23. PMID:24152047 doi:https://dx.doi.org/10.1021/bi4011754

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