4nbl: Difference between revisions

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-'''Unreleased structure'''
+{{STRUCTURE_4nbl|  PDB=4nbl  |  SCENE=  }}
+===Tailoring Small Molecules for an Allosteric Site on Procaspase-6===
+{{ABSTRACT_PUBMED_24259468}}
-The entry 4nbl is ON HOLD
+==Function==
+[[http://www.uniprot.org/uniprot/CASP6_HUMAN CASP6_HUMAN]] Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes programmed cell death.
-Authors: Murray, J.M., Steffek, M.
+==About this Structure==
+[[4nbl]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NBL OCA].
-Description: Tailoring Small Molecules for an Allosteric Site on Procaspase-6
+==Reference==
+<ref group="xtra">PMID:024259468</ref><references group="xtra"/><references/>
+[[Category: Caspase-6]]
+[[Category: Murray, J M.]]
+[[Category: Steffek, M.]]
+[[Category: Allosteric]]
+[[Category: Caspase]]
+[[Category: Caspase-6 zymogen]]
+[[Category: Cysteine protease]]
+[[Category: Hydrolase-hydrolase inhibitor complex]]
+[[Category: Procaspse-6]]
+[[Category: Structure based drug design]]

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