4m1m: Difference between revisions
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==About this Structure== | ==About this Structure== | ||
[[4m1m]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M1M OCA]. | [[4m1m]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M1M OCA]. | ||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID:024155053</ref><references group="xtra"/><references/> | <ref group="xtra">PMID:024155053</ref><references group="xtra"/><references/> | ||
[[Category: Lk3 transgenic mice]] | |||
[[Category: Xenobiotic-transporting ATPase]] | [[Category: Xenobiotic-transporting ATPase]] | ||
[[Category: Aller, S G.]] | [[Category: Aller, S G.]] | ||
Revision as of 10:50, 1 January 2014
Corrected Structure of Mouse P-glycoprotein
Template:ABSTRACT PUBMED 24155053
Function
[MDR1A_MOUSE] Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells.[1]
About this Structure
4m1m is a 2 chain structure with sequence from Lk3 transgenic mice. Full crystallographic information is available from OCA.
Reference
- Li J, Jaimes KF, Aller SG. Refined structures of mouse P-Glycoprotein. Protein Sci. 2013 Oct 24. doi: 10.1002/pro.2387. PMID:24155053 doi:https://dx.doi.org/10.1002/pro.2387
- ↑ Aller SG, Yu J, Ward A, Weng Y, Chittaboina S, Zhuo R, Harrell PM, Trinh YT, Zhang Q, Urbatsch IL, Chang G. Structure of P-glycoprotein reveals a molecular basis for poly-specific drug binding. Science. 2009 Mar 27;323(5922):1718-22. PMID:19325113 doi:323/5922/1718
