2q3z: Difference between revisions

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[[Image:2q3z.jpg|left|200px]]<br /><applet load="2q3z" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2q3z.jpg|left|200px]]
caption="2q3z, resolution 2.000&Aring;" />
 
'''Transglutaminase 2 undergoes large conformational change upon activation'''<br />
{{Structure
|PDB= 2q3z |SIZE=350|CAPTION= <scene name='initialview01'>2q3z</scene>, resolution 2.000&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene> and <scene name='pdbligand=NH2:AMINO GROUP'>NH2</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Protein-glutamine_gamma-glutamyltransferase Protein-glutamine gamma-glutamyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.2.13 2.3.2.13]
|GENE= TGM2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''Transglutaminase 2 undergoes large conformational change upon activation'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2Q3Z is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=SO4:'>SO4</scene>, <scene name='pdbligand=ACE:'>ACE</scene> and <scene name='pdbligand=NH2:'>NH2</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Protein-glutamine_gamma-glutamyltransferase Protein-glutamine gamma-glutamyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.2.13 2.3.2.13] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Q3Z OCA].  
2Q3Z is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Q3Z OCA].  


==Reference==
==Reference==
Transglutaminase 2 undergoes a large conformational change upon activation., Pinkas DM, Strop P, Brunger AT, Khosla C, PLoS Biol. 2007 Dec;5(12):e327. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=18092889 18092889]
Transglutaminase 2 undergoes a large conformational change upon activation., Pinkas DM, Strop P, Brunger AT, Khosla C, PLoS Biol. 2007 Dec;5(12):e327. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18092889 18092889]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Protein-glutamine gamma-glutamyltransferase]]
[[Category: Protein-glutamine gamma-glutamyltransferase]]
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[[Category: transglutaminase 2]]
[[Category: transglutaminase 2]]


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