4k06: Difference between revisions

Revision as of 09:01, 27 November 2013

4k06 is a 2 chain structure with sequence from Bothrops brazili. Full crystallographic information is available from OCA.

Fernandes CA, Comparetti EJ, Borges RJ, Huancahuire-Vega S, Ponce-Soto LA, Marangoni S, Soares AM, Fontes MR. Structural bases for a complete myotoxic mechanism: Crystal structures of two non-catalytic phospholipases A-like from Bothrops brazili venom. Biochim Biophys Acta. 2013 Oct 18;1834(12):2772-2781. doi:, 10.1016/j.bbapap.2013.10.009. PMID:24145104 doi:https://dx.doi.org/10.1016/j.bbapap.2013.10.009

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 ===Crystal structure of MTX-II from Bothrops brazili venom complexed with polyethylene glycol===
 {{ABSTRACT_PUBMED_24145104}}
-==Function==
-[[http://www.uniprot.org/uniprot/PA2B1_BOTJR PA2B1_BOTJR]] Snake venom phospholipase A2 homolog that lacks enzymatic activity. In vivo, induces muscle necrosis, accompanied by polymorphonuclear cell infiltration, and edema in the mouse paw. Damages artificial and myoblast membranes by a calcium-independent mechanism. Has bactericidal activity.<ref>PMID:3176051</ref> <ref>PMID:11018293</ref> <ref>PMID:11829743</ref> <ref>PMID:12079495</ref> <ref>PMID:17346668</ref> <ref>PMID:18160090</ref> <ref>PMID:17157889</ref>
 ==About this Structure==
-[[4k06]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bothrops_jararacussu Bothrops jararacussu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K06 OCA].
+[[4k06]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bothrops_brazili Bothrops brazili]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K06 OCA].
 ==Reference==
 <ref group="xtra">PMID:024145104</ref><references group="xtra"/><references/>
-[[Category: Bothrops jararacussu]]
+[[Category: Bothrops brazili]]
 [[Category: Borges, R J.]]
 [[Category: Comparetti, E J.]]