2m5i: Difference between revisions
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==About this Structure== | ==About this Structure== | ||
[[2m5i]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2M5I OCA]. | [[2m5i]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2M5I OCA]. | ||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID:024158446</ref><references group="xtra"/><references/> | <ref group="xtra">PMID:024158446</ref><references group="xtra"/><references/> | ||
[[Category: Human]] | |||
[[Category: Tjandra, N.]] | [[Category: Tjandra, N.]] | ||
[[Category: Wang, Y.]] | [[Category: Wang, Y.]] | ||
Revision as of 10:55, 1 January 2014
NMR structures of human apoptotic protein tBid in LPPG micelle
Template:ABSTRACT PUBMED 24158446
Function
[BID_HUMAN] The major proteolytic product p15 BID allows the release of cytochrome c (By similarity). Isoform 1, isoform 2 and isoform 4 induce ICE-like proteases and apoptosis. Isoform 3 does not induce apoptosis. Counters the protective effect of Bcl-2.[1]
About this Structure
2m5i is a 1 chain structure with sequence from Human. Full experimental information is available from OCA.
Reference
- Wang Y, Tjandra N. Structural insights of tBid, the caspase-8 activated Bid, and its BH3 domain. J Biol Chem. 2013 Oct 24. PMID:24158446 doi:https://dx.doi.org/10.1074/jbc.M113.503680
- ↑ Renshaw SA, Dempsey CE, Barnes FA, Bagstaff SM, Dower SK, Bingle CD, Whyte MK. Three novel Bid proteins generated by alternative splicing of the human Bid gene. J Biol Chem. 2004 Jan 23;279(4):2846-55. Epub 2003 Oct 28. PMID:14583606 doi:https://dx.doi.org/10.1074/jbc.M309769200
