2q61: Difference between revisions

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[[Image:2q61.jpg|left|200px]]<br /><applet load="2q61" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2q61.jpg|left|200px]]
caption="2q61, resolution 2.197&Aring;" />
 
'''Crystal Structure of PPARgamma ligand binding domain bound to partial agonist SR145'''<br />
{{Structure
|PDB= 2q61 |SIZE=350|CAPTION= <scene name='initialview01'>2q61</scene>, resolution 2.197&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=SF1:1-BENZYL-5-CHLORO-3-(PHENYLTHIO)-1H-INDOLE-2-CARBOXYLIC ACID'>SF1</scene>
|ACTIVITY=
|GENE= PPARG, NR1C3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''Crystal Structure of PPARgamma ligand binding domain bound to partial agonist SR145'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2Q61 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=SF1:'>SF1</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Q61 OCA].  
2Q61 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Q61 OCA].  


==Reference==
==Reference==
Partial agonists activate PPARgamma using a helix 12 independent mechanism., Bruning JB, Chalmers MJ, Prasad S, Busby SA, Kamenecka TM, He Y, Nettles KW, Griffin PR, Structure. 2007 Oct;15(10):1258-71. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17937915 17937915]
Partial agonists activate PPARgamma using a helix 12 independent mechanism., Bruning JB, Chalmers MJ, Prasad S, Busby SA, Kamenecka TM, He Y, Nettles KW, Griffin PR, Structure. 2007 Oct;15(10):1258-71. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17937915 17937915]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: protein-ligand complex]]
[[Category: protein-ligand complex]]


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