2q6j: Difference between revisions

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[[Image:2q6j.gif|left|200px]]<br /><applet load="2q6j" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2q6j.gif|left|200px]]
caption="2q6j, resolution 2.700&Aring;" />
 
'''Crystal Structure of Estrogen Receptor alpha Complexed to a B-N Substituted Ligand'''<br />
{{Structure
|PDB= 2q6j |SIZE=350|CAPTION= <scene name='initialview01'>2q6j</scene>, resolution 2.700&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=A48:4-[(DIMESITYLBORYL)(2,2,2-TRIFLUOROETHYL)AMINO]PHENOL'>A48</scene>
|ACTIVITY=
|GENE= ESR1, ESR, NR3A1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]), Ncoa2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus])
}}
 
'''Crystal Structure of Estrogen Receptor alpha Complexed to a B-N Substituted Ligand'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2Q6J is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus] with <scene name='pdbligand=A48:'>A48</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Q6J OCA].  
2Q6J is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Q6J OCA].  


==Reference==
==Reference==
Elemental isomerism: a boron-nitrogen surrogate for a carbon-carbon double bond increases the chemical diversity of estrogen receptor ligands., Zhou HB, Nettles KW, Bruning JB, Kim Y, Joachimiak A, Sharma S, Carlson KE, Stossi F, Katzenellenbogen BS, Greene GL, Katzenellenbogen JA, Chem Biol. 2007 Jun;14(6):659-69. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17584613 17584613]
Elemental isomerism: a boron-nitrogen surrogate for a carbon-carbon double bond increases the chemical diversity of estrogen receptor ligands., Zhou HB, Nettles KW, Bruning JB, Kim Y, Joachimiak A, Sharma S, Carlson KE, Stossi F, Katzenellenbogen BS, Greene GL, Katzenellenbogen JA, Chem Biol. 2007 Jun;14(6):659-69. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17584613 17584613]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: protein-ligand complex]]
[[Category: protein-ligand complex]]


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