2q72: Difference between revisions

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[[Image:2q72.jpg|left|200px]]<br /><applet load="2q72" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2q72.jpg|left|200px]]
caption="2q72, resolution 1.70&Aring;" />
 
'''Crystal Structure Analysis of LeuT complexed with L-leucine, sodium, and imipramine'''<br />
{{Structure
|PDB= 2q72 |SIZE=350|CAPTION= <scene name='initialview01'>2q72</scene>, resolution 1.70&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=BOG:B-OCTYLGLUCOSIDE'>BOG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=LEU:LEUCINE'>LEU</scene> and <scene name='pdbligand=IXX:3-(5H-DIBENZO[B,F]AZEPIN-5-YL)-N,N-DIMETHYLPROPAN-1-AMINE'>IXX</scene>
|ACTIVITY=
|GENE= snf ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=63363 Aquifex aeolicus])
}}
 
'''Crystal Structure Analysis of LeuT complexed with L-leucine, sodium, and imipramine'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2Q72 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Aquifex_aeolicus Aquifex aeolicus] with <scene name='pdbligand=BOG:'>BOG</scene>, <scene name='pdbligand=NA:'>NA</scene>, <scene name='pdbligand=LEU:'>LEU</scene> and <scene name='pdbligand=IXX:'>IXX</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Q72 OCA].  
2Q72 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Aquifex_aeolicus Aquifex aeolicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Q72 OCA].  


==Reference==
==Reference==
Antidepressant binding site in a bacterial homologue of neurotransmitter transporters., Singh SK, Yamashita A, Gouaux E, Nature. 2007 Aug 23;448(7156):952-6. Epub 2007 Aug 8. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17687333 17687333]
Antidepressant binding site in a bacterial homologue of neurotransmitter transporters., Singh SK, Yamashita A, Gouaux E, Nature. 2007 Aug 23;448(7156):952-6. Epub 2007 Aug 8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17687333 17687333]
[[Category: Aquifex aeolicus]]
[[Category: Aquifex aeolicus]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: tricyclic antidepressant]]
[[Category: tricyclic antidepressant]]


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