2q80: Difference between revisions

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[[Image:2q80.jpg|left|200px]]<br /><applet load="2q80" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2q80.jpg|left|200px]]
caption="2q80, resolution 2.70&Aring;" />
 
'''Crystal structure of human geranylgeranyl pyrophosphate synthase bound to GGPP'''<br />
{{Structure
|PDB= 2q80 |SIZE=350|CAPTION= <scene name='initialview01'>2q80</scene>, resolution 2.70&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene> and <scene name='pdbligand=GRG:GERANYLGERANYL DIPHOSPHATE'>GRG</scene>
|ACTIVITY=
|GENE= GGPS1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''Crystal structure of human geranylgeranyl pyrophosphate synthase bound to GGPP'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2Q80 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=MG:'>MG</scene> and <scene name='pdbligand=GRG:'>GRG</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. This structure supersedes the now removed PDB entry 2FVI. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Q80 OCA].  
2Q80 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry 2FVI. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Q80 OCA].  


==Reference==
==Reference==
The crystal structure of human geranylgeranyl pyrophosphate synthase reveals a novel hexameric arrangement and inhibitory product binding., Kavanagh KL, Dunford JE, Bunkoczi G, Russell RG, Oppermann U, J Biol Chem. 2006 Aug 4;281(31):22004-12. Epub 2006 May 11. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16698791 16698791]
The crystal structure of human geranylgeranyl pyrophosphate synthase reveals a novel hexameric arrangement and inhibitory product binding., Kavanagh KL, Dunford JE, Bunkoczi G, Russell RG, Oppermann U, J Biol Chem. 2006 Aug 4;281(31):22004-12. Epub 2006 May 11. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16698791 16698791]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: isoprenoid pathway]]
[[Category: isoprenoid pathway]]
[[Category: sgc]]
[[Category: sgc]]
[[Category: structural genomics]]
[[Category: structural genomic]]
[[Category: structural genomics consortium]]
[[Category: structural genomics consortium]]


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